Literature DB >> 30359710

An Infertile Couple's Long and Expensive Path to Varicocele Repair.

Adithya Balasubramanian1, Nannan Thirumavalavan2, Jason M Scovell1, Jonathan Lo1, Byung Ji1, Elizabeth L Godfrey1, Alexander W Pastuszak1, Larry I Lipshultz1.   

Abstract

OBJECTIVE: To characterize the pathways to care that infertile couples requiring varicocele repair (VR) pursue prior to presenting to a male fertility clinic.
METHODS: An IRB-approved single center retrospective review of patients undergoing VR after presentation to an academic male fertility clinic was performed. Patients whose charts included partner histories were assessed for duration of attempting conception, prior workup, and assisted reproductive technology (ART) use.
RESULTS: A total of 405 couples were included. At presentation, mean age was 34.4 (SD ± 6.5) years for men and 31.1 (SD ± 4.3) years for women (P < .0001). A couple's first visit to a physician was a gynecologist in 59% (198/334) of couples, a reproductive endocrinologist (REI) in 25% (83/334) of cases, with 14% (47/334) presenting without a previous female workup and were self-referred, and 2% (6/334) seeing both a gynecologist and REI prior to presentation. On average, couples attempted pregnancy for 22.3 (SD ± 21.1, range 0-120) months prior to presentation. Eighteen percent of couples underwent ART prior to presentation. Couples who had undergone ART had lower pre-VR total motile sperm counts compared to couples not pursuing ART prior to presentation (P = 0.031). The majority (70.4%) of females had no abnormality in their workup, making varicocele the only correctable factor for infertility in the couple.
CONCLUSIONS: Our findings show a significant delay in referral of infertile men requiring VR. Eighteen percent of couples underwent costly ART prior to an inexpensive male workup. In an era of medical cost containment, early referral to a male infertility specialist is imperative.
Copyright © 2018. Published by Elsevier Inc.

Entities:  

Mesh:

Year:  2018        PMID: 30359710      PMCID: PMC6387868          DOI: 10.1016/j.urology.2018.10.021

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  27 in total

1.  Can varicocelectomy significantly change the way couples use assisted reproductive technologies?

Authors:  Selahittin Cayan; Fikret Erdemir; Isa Ozbey; Paul J Turek; Ateş Kadioğlu; Sedat Tellaloğlu
Journal:  J Urol       Date:  2002-04       Impact factor: 7.450

2.  The Impact of Microsurgical Repair of Subclinical and Clinical Varicoceles on Total Motile Sperm Count: Is There a Difference?

Authors:  Nannan Thirumavalavan; Jason M Scovell; Adithya Balasubramanian; Taylor P Kohn; Byung Ji; Asad Hasan; Alexander W Pastuszak; Larry I Lipshultz
Journal:  Urology       Date:  2018-07-05       Impact factor: 2.649

3.  Diagnostic evaluation of the infertile male: a committee opinion.

Authors: 
Journal:  Fertil Steril       Date:  2015-01-15       Impact factor: 7.329

4.  Varicocelectomy improves intrauterine insemination success rates in men with varicocele.

Authors:  J A Daitch; M A Bedaiwy; E B Pasqualotto; B N Hendin; J Hallak; T Falcone; A J Thomas; D R Nelson; A Agarwal
Journal:  J Urol       Date:  2001-05       Impact factor: 7.450

5.  Practice patterns in vasectomy reversal surgery: results of a questionnaire study among practicing urologists.

Authors:  Donald S Crain; James L Roberts; Christopher L Amling
Journal:  J Urol       Date:  2004-01       Impact factor: 7.450

6.  Does varicocele grade determine extent of alteration to spermatogenesis in adolescents?

Authors:  Marcos Mitsuyoshi Mori; Ricardo Pimenta Bertolla; Renato Fraietta; Valdemar Ortiz; Agnaldo Pereira Cedenho
Journal:  Fertil Steril       Date:  2007-12-31       Impact factor: 7.329

7.  Sperm retrieval and intracytoplasmic sperm injection in men with nonobstructive azoospermia, and treated and untreated varicocele.

Authors:  Kubilay Inci; Metin Hascicek; Onder Kara; Ayse Veyhurda Dikmen; Timur Gürgan; Ali Ergen
Journal:  J Urol       Date:  2009-08-15       Impact factor: 7.450

8.  Practice patterns in the surgical approach for adolescent varicocelectomy.

Authors:  Miriam Harel; Katherine W Herbst; Eric Nelson
Journal:  Springerplus       Date:  2015-12-14

Review 9.  Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.

Authors:  Ashok Agarwal; Ahmad Majzoub; Sandro C Esteves; Edmund Ko; Ranjith Ramasamy; Armand Zini
Journal:  Transl Androl Urol       Date:  2016-12

Review 10.  Prediction of male infertility by the World Health Organization laboratory manual for assessment of semen analysis: A systematic review.

Authors:  Amir S Patel; Joon Yau Leong; Ranjith Ramasamy
Journal:  Arab J Urol       Date:  2017-11-20
View more
  1 in total

1.  Jiawei Runjing Decoction Improves Spermatogenesis of Cryptozoospermia With Varicocele by Regulating the Testicular Microenvironment: Two-Center Prospective Cohort Study.

Authors:  Huang Liu; Zhongwang Huang; Houbin Zheng; Zhiyong Zhu; Hui Yang; Xingzhang Liu; Tao Pang; Liping He; Hai Lin; Lei Hu; Qingqi Zeng; Lanying Han
Journal:  Front Pharmacol       Date:  2022-08-09       Impact factor: 5.988

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.