Literature DB >> 19888307

How do transcription factors select specific binding sites in the genome?

Yongping Pan1, Chung-Jung Tsai, Buyong Ma, Ruth Nussinov.   

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Year:  2009        PMID: 19888307      PMCID: PMC6416780          DOI: 10.1038/nsmb1109-1118

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN: 1545-9985            Impact factor:   15.369


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  26 in total

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5.  Amplification of signaling via cellular allosteric relay and protein disorder.

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6.  DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseases.

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7.  Allostery: DNA does it, too.

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8.  The plasticity of estrogen receptor-DNA complexes: binding affinity and specificity of estrogen receptors to estrogen response element half-sites separated by variant spacers.

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Review 9.  ASPP: a new family of oncogenes and tumour suppressor genes.

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10.  The mechanism of ubiquitination in the cullin-RING E3 ligase machinery: conformational control of substrate orientation.

Authors:  Jin Liu; Ruth Nussinov
Journal:  PLoS Comput Biol       Date:  2009-10-02       Impact factor: 4.475

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  19 in total

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Review 2.  Gene-specific transcription activation via long-range allosteric shape-shifting.

Authors:  Chung-Jung Tsai; Ruth Nussinov
Journal:  Biochem J       Date:  2011-10-01       Impact factor: 3.857

Review 3.  Understanding biomolecular motion, recognition, and allostery by use of conformational ensembles.

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Review 4.  Diversity, versatility and complexity of bacterial gene regulation mechanisms: opportunities and drawbacks for applications in synthetic biology.

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5.  Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements.

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6.  Dipeptide analysis of p53 mutations and evolution of p53 family proteins.

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7.  Why does binding of proteins to DNA or proteins to proteins not necessarily spell function?

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8.  Predicting protein-DNA interactions by full search computational docking.

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Review 10.  Mechanisms of transcription factor selectivity.

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Journal:  Trends Genet       Date:  2010-01-13       Impact factor: 11.639

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