Literature DB >> 19885721

Prenatal testing for Down syndrome: comparison of screening practices in the UK and USA.

Dagmar Tapon1.   

Abstract

Prenatal testing for Down Syndrome is a topic covered in every genetic counselor's training as it constitutes the main workload of genetic counselors in prenatal settings. Most Western countries nowadays offer some type of testing for Down Syndrome. However, practices vary according to country with regards to what tests are offered, insurance coverage and the legal situation concerning the option of terminating an affected pregnancy. In view of the growing interest in international genetic counseling issues, this article aims to compare prenatal testing practices in two English-speaking countries: the United Kingdom and the United States of America. A case will be presented to highlight some of the differences in practice. The topic underlines important implications for genetic counseling practice, such as patients' understanding of testing practices, risk perception, counseling provision and impact of prenatal testing results.

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Year:  2009        PMID: 19885721     DOI: 10.1007/s10897-009-9269-1

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  106 in total

1.  Genetic amniocentesis complications: is the incidence overrated?

Authors:  Anwar H Nassar; Dibe Martin; Victor Hugo González-Quintero; Orlando Gómez-Marín; Fawwaz Salman; Alfredo Gutierrez; Mary J O'Sullivan
Journal:  Gynecol Obstet Invest       Date:  2004-06-02       Impact factor: 2.031

2.  First-trimester nasal bone evaluation for aneuploidy in the general population.

Authors:  Fergal D Malone; Robert H Ball; David A Nyberg; Christine H Comstock; George Saade; Richard L Berkowitz; Lorraine Dugoff; Sabrina D Craigo; Stephen R Carr; Honor M Wolfe; Tara Tripp; Mary E D'Alton
Journal:  Obstet Gynecol       Date:  2004-12       Impact factor: 7.661

Review 3.  Practitioner review: stress intervention for parents of children with intellectual disabilities.

Authors:  Richard P Hastings; Alexandra Beck
Journal:  J Child Psychol Psychiatry       Date:  2004-11       Impact factor: 8.982

Review 4.  The use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosis.

Authors:  Caroline F Wright; Hilary Burton
Journal:  Hum Reprod Update       Date:  2008-10-22       Impact factor: 15.610

5.  Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis.

Authors:  R Smith-Bindman; W Hosmer; V A Feldstein; J J Deeks; J D Goldberg
Journal:  JAMA       Date:  2001-02-28       Impact factor: 56.272

6.  Fetal nuchal translucency: ultrasound screening for fetal trisomy in the first trimester of pregnancy.

Authors:  K H Nicolaides; M L Brizot; R J Snijders
Journal:  Br J Obstet Gynaecol       Date:  1994-09

7.  Accepting or declining the offer of prenatal screening for congenital defects: test uptake and women's reasons.

Authors:  Matthijs van den Berg; Danielle R M Timmermans; Johanna H Kleinveld; Elisa Garcia; John M G van Vugt; Gerrit van der Wal
Journal:  Prenat Diagn       Date:  2005-01       Impact factor: 3.050

8.  Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening.

Authors:  K H Nicolaides; K Spencer; K Avgidou; S Faiola; O Falcon
Journal:  Ultrasound Obstet Gynecol       Date:  2005-03       Impact factor: 7.299

9.  Recurrences of free trisomy 21: analysis of data from the National Down Syndrome Cytogenetic Register.

Authors:  J K Morris; D E Mutton; E Alberman
Journal:  Prenat Diagn       Date:  2005-12       Impact factor: 3.050

10.  'Balance' is in the eye of the beholder: providing information to support informed choices in antenatal screening via Antenatal Screening Web Resource.

Authors:  Shenaz Ahmed; Louise Bryant; Jenny Hewison
Journal:  Health Expect       Date:  2007-12       Impact factor: 3.377

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  7 in total

1.  Rates of prenatal screening across health care regions in Ontario, Canada: a retrospective cohort study.

Authors:  Robin Z Hayeems; Michael Campitelli; Xiaomu Ma; Tianhua Huang; Mark Walker; Astrid Guttmann
Journal:  CMAJ Open       Date:  2015-04-02

2.  Rapid aneuploidy detection or karyotyping? Ethical reflection.

Authors:  Antina de Jong; Wybo J Dondorp; Daniëlle R M Timmermans; Jan M M van Lith; Guido M W R de Wert
Journal:  Eur J Hum Genet       Date:  2011-06-01       Impact factor: 4.246

Review 3.  Advances in prenatal screening: the ethical dimension.

Authors:  Antina de Jong; Wybo J Dondorp; Suzanna G M Frints; Christine E M de Die-Smulders; Guido M W R de Wert
Journal:  Nat Rev Genet       Date:  2011-08-18       Impact factor: 53.242

4.  Is preparation a good reason for prenatal genetic testing? Ethical and critical questions.

Authors:  Marsha Michie
Journal:  Birth Defects Res       Date:  2020-03-01       Impact factor: 2.344

5.  The scope of prenatal diagnosis for women at increased risk for aneuploidies: views and preferences of professionals and potential users.

Authors:  Antina de Jong; Wybo J Dondorp; Anja Krumeich; Julie Boonekamp; Jan M M van Lith; Guido M W R de Wert
Journal:  J Community Genet       Date:  2012-11-09

6.  Pregnant Hispanic women's views and knowledge of prenatal genetic testing.

Authors:  Robin L Page; Christina Murphey; Yahyahan Aras; Lei-Shih Chen; Ryan Loftin
Journal:  J Genet Couns       Date:  2021-01-26       Impact factor: 2.537

7.  Is routine prenatal screening and testing fundamentally incompatible with a commitment to reproductive choice? Learning from the historical context.

Authors:  Panagiota Nakou
Journal:  Med Health Care Philos       Date:  2020-10-30
  7 in total

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