Literature DB >> 19870799

CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : XII. THE IMMUNOLOGICAL PROPERTIES OF AN ARTIFICIAL ANTIGEN CONTAINING CELLOBIURONIC ACID.

W F Goebel1.   

Abstract

1. Artificial antigens containing the azobenzyl glycosides of the disaccharide cellobiose and the aldobionic acid, cellobiuronic acid, give rise in rabbits to antibodies which are specific and characteristic of the saccharide constituent. The antiserum to cellobiuronic acid shows broader serological cross reactions than does that to cellobiose. 2. An antiserum to the cellobiuronic acid antigen precipitates the capsular polysaccharide of Type III Pneumococcus when the latter is combined with a heterologous protein. 3. The cellobiuronic acid test antigen precipitates vigorously in antipneumococcus sera Types II, III, and VIII. The mechanism of these reactions is discussed.

Entities:  

Year:  1938        PMID： 19870799      PMCID： PMC2133695          DOI： 10.1084/jem.68.4.469

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  5 in total

1.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : IV. THE SYNTHESIS OF THEp-AMINOBENZYL ETHER OF THE SOLUBLE SPECIFIC SUBSTANCE OF TYPE III PNEUMOCOCCUS AND ITS COUPLING WITH PROTEIN.

Authors:  W F Goebel; O T Avery
Journal:  J Exp Med       Date:  1931-07-31       Impact factor: 14.307

2.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : XI. THE SPECIFICITY OF AZOPROTEIN ANTIGENS CONTAINING GLUCURONIC AND GALACTURONIC ACIDS.

Authors:  W F Goebel; R D Hotchkiss
Journal:  J Exp Med       Date:  1937-07-31       Impact factor: 14.307

3.  STUDIES ON THE PRECIPITIN REACTION : PRECIPITATING HAPTENS; SPECIES DIFFERENCES IN ANTIBODIES.

Authors:  M Heidelberger; F E Kendall
Journal:  J Exp Med       Date:  1933-02-28       Impact factor: 14.307

4.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : VIII. THE INFLUENCE OF THE ACETYL GROUP ON THE SPECIFICITY OF HEXOSIDE-PROTEIN ANTIGENS.

Authors:  W F Goebel; F H Babers; O T Avery
Journal:  J Exp Med       Date:  1934-06-30       Impact factor: 14.307

5.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : IX. THE SPECIFICITY OF ANTIGENS PREPARED BY COMBINING THEp-AMINOPHENOL GLYCOSIDES OF DISACCHARIDES WITH PROTEIN.

Authors:  W F Goebel; O T Avery; F H Babers
Journal:  J Exp Med       Date:  1934-10-31       Impact factor: 14.307
  5 in total
  8 in total

1.  Immunochemical properties of oligosaccharide-protein conjugates with Klebsiella-K2 specificity. I. Specificity and crossreactivity of anti-conjugate versus anti-bacterial antibodies.

Authors:  H Geyer; S Stirm; K Himmelspach
Journal:  Med Microbiol Immunol       Date:  1979-01-24       Impact factor: 3.402

2.  Synthetic oligosaccharides as tools to demonstrate cross-reactivity between polysaccharide antigens.

Authors:  Vince Pozsgay; Joanna Kubler-Kielb; Bruce Coxon; Paul Santacroce; John B Robbins; Rachel Schneerson
Journal:  J Org Chem       Date:  2012-06-29       Impact factor: 4.354

3.  Antibody responses to Haemophilus influenzae type b and diphtheria toxin induced by conjugates of oligosaccharides of the type b capsule with the nontoxic protein CRM197.

Authors:  P Anderson
Journal:  Infect Immun       Date:  1983-01       Impact factor: 3.441

4.  Immunogens consisting of oligosaccharides from the capsule of Haemophilus influenzae type b coupled to diphtheria toxoid or the toxin protein CRM197.

Authors:  P Anderson; M E Pichichero; R A Insel
Journal:  J Clin Invest       Date:  1985-07       Impact factor: 14.808

5.  Immune response of neonates to pneumococcal polysaccharide-protein conjugate.

Authors:  K T Lin; C J Lee
Journal:  Immunology       Date:  1982-06       Impact factor: 7.397

6.  The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella.

Authors:  Robert M F van der Put; Carolien Smitsman; Alex de Haan; Martin Hamzink; Hans Timmermans; Joost Uittenbogaard; Janny Westdijk; Michiel Stork; Olga Ophorst; Françoise Thouron; Catherine Guerreiro; Philippe J Sansonetti; Armelle Phalipon; Laurence A Mulard
Journal:  ACS Cent Sci       Date:  2022-03-17       Impact factor: 18.728

7.  CROSS-REACTIONS OF PNEUMOCOCCAL TYPES. QUANTITATIVE STUDIES WITH THE CAPSULAR POLYSACCHARIDES.

Authors:  M HEIDELBERGER; J M TYLER
Journal:  J Exp Med       Date:  1964-11-01       Impact factor: 14.307

8.  STUDIES ON ANTIBACTERIAL IMMUNITY INDUCED BY ARTIFICIAL ANTIGENS : I. IMMUNITY TO EXPERIMENTAL PNEUMOCOCCAL INFECTION WITH AN ANTIGEN CONTAINING CELLOBIURONIC ACID.

Authors:  W F Goebel
Journal:  J Exp Med       Date:  1939-02-28       Impact factor: 14.307
  8 in total

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