Literature DB >> 19870851

STUDIES ON ANTIBACTERIAL IMMUNITY INDUCED BY ARTIFICIAL ANTIGENS : I. IMMUNITY TO EXPERIMENTAL PNEUMOCOCCAL INFECTION WITH AN ANTIGEN CONTAINING CELLOBIURONIC ACID.

W F Goebel1.   

Abstract

1. An artificial antigen containing the azobenzyl glycoside of cellobiuronic acid gives rise in rabbits to antibodies which: (a) give the Neufeld reaction and agglutinate Type III pneumococci, (b) confer passive protection on mice against infection with Types II, III, and VIII pneumococci. 2. Rabbits immunized with the artificial cellobiuronic acid antigen acquire active resistance to infection with virulent Type III pneumococci. 3. The antibodies evoked by an antigen containing the azobenzyl glycoside of cellobiose exhibit none of these phenomena.

Entities:  

Year:  1939        PMID： 19870851      PMCID： PMC2133744          DOI： 10.1084/jem.69.3.353

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  3 in total

1.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : XII. THE IMMUNOLOGICAL PROPERTIES OF AN ARTIFICIAL ANTIGEN CONTAINING CELLOBIURONIC ACID.

Authors:  W F Goebel
Journal:  J Exp Med       Date:  1938-09-30       Impact factor: 14.307

2.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : V. THE IMMUNOLOGICAL SPECIFITY OF AN ANTIGEN PREPARED BY COMBINING THE CAPSULAR POLYSACCHARIDE OF TYPE III PNEUMOCOCCUS WITH FOREIGN PROTEIN.

Authors:  O T Avery; W F Goebel
Journal:  J Exp Med       Date:  1931-07-31       Impact factor: 14.307

3.  THE EVALUATION OF ACTIVE RESISTANCE TO PNEUMOCOCCUS INFECTION IN RABBITS.

Authors:  K Goodner; E G Stillman
Journal:  J Exp Med       Date:  1933-07-31       Impact factor: 14.307
  3 in total
  14 in total

Review 1.  Immunogenicity and immunochemistry of Streptococcus pneumoniae capsular polysaccharides.

Authors:  J E van Dam; A Fleer; H Snippe
Journal:  Antonie Van Leeuwenhoek       Date:  1990-06       Impact factor: 2.271

2.  Immunochemical properties of oligosaccharide-protein conjugates with Klebsiella-K2 specificity. I. Specificity and crossreactivity of anti-conjugate versus anti-bacterial antibodies.

Authors:  H Geyer; S Stirm; K Himmelspach
Journal:  Med Microbiol Immunol       Date:  1979-01-24       Impact factor: 3.402

3.  Nonionic block polymer surfactants modulate the humoral immune response against Streptococcus pneumoniae-derived hexasaccharide-protein conjugates.

Authors:  G J Zigterman; K Schotanus; E B Ernste; G J Van Dam; M Jansze; H Snippe; J M Willers
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

4.  Immunogenic properties in mice of hexasaccharide from the capsular polysaccharide of Streptococcus pneumoniae type 3.

Authors:  H Snippe; A J van Houte; J E van Dam; M J De Reuver; M Jansze; J M Willers
Journal:  Infect Immun       Date:  1983-06       Impact factor: 3.441

5.  New approaches for control of infections using synthetic or semi-synthetic constructs containing MDP.

Authors:  L Chedid; F Audibert
Journal:  Springer Semin Immunopathol       Date:  1985

6.  Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody.

Authors:  B Vulliez-Le Normand; F A Saul; A Phalipon; F Bélot; C Guerreiro; L A Mulard; G A Bentley
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-10       Impact factor: 11.205

Review 7.  Pneumococcal vaccination and revaccination of older adults.

Authors:  Andrew S Artz; William B Ershler; Dan L Longo
Journal:  Clin Microbiol Rev       Date:  2003-04       Impact factor: 26.132

8.  Immunochemical properties of oligosaccharide-protein conjugates with Klebsiella-K2-specificity. II. Protective capacity of the conjugates and anti-conjugate antibodies against infection with Klebsiella pneumoniae 01:K2 in mice.

Authors:  H Geyer; S Schlecht; K Himmelspach
Journal:  Med Microbiol Immunol       Date:  1982       Impact factor: 3.402

Review 9.  Streptococcus pneumoniae: virulence factors, pathogenesis, and vaccines.

Authors:  E AlonsoDeVelasco; A F Verheul; J Verhoef; H Snippe
Journal:  Microbiol Rev       Date:  1995-12

10.  Immunogenic properties of octasaccharide-protein conjugates derived from Klebsiella serotype 11 capsular polysaccharide.

Authors:  J W Zigterman; J E van Dam; H Snippe; F T Rotteveel; M Jansze; J M Willers; J P Kamerling; J F Vliegenthart
Journal:  Infect Immun       Date:  1985-02       Impact factor: 3.441
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