Literature DB >> 19870325

CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : IX. THE SPECIFICITY OF ANTIGENS PREPARED BY COMBINING THEp-AMINOPHENOL GLYCOSIDES OF DISACCHARIDES WITH PROTEIN.

W F Goebel1, O T Avery, F H Babers.   

Abstract

The results of the present study indicate that by means of serological reactions it is possible to differentiate selectively the p-aminophenol glycosides of maltose, cellobiose, gentiobiose, and lactose. The immunological specificity of disaccharide-protein antigens prepared from these derivatives, irrespective of the nature of the conjoined protein, is determined by (1) the glycoside molecule as a whole, (2) the configuration of the terminal hexose molecule, and (3) the position of linkage of the two hexose units in the carbohydrate radical. The specificity of the antibodies induced by the disaccharide antigens appears to be more sharply defined when the configuration of the terminal hexose is of the beta rather than of the alpha type.

Entities:  

Year:  1934        PMID: 19870325      PMCID: PMC2132428          DOI: 10.1084/jem.60.5.599

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  5 in total

1.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : II. IMMUNOLOGICAL SPECIFICITY OF SYNTHETIC SUGAR-PROTEIN ANTIGENS.

Authors:  O T Avery; W F Goebel
Journal:  J Exp Med       Date:  1929-09-30       Impact factor: 14.307

2.  QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE ROLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION.

Authors:  M Heidelberger; F E Kendall
Journal:  J Exp Med       Date:  1934-03-31       Impact factor: 14.307

3.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : VII. IMMUNOLOGICAL SPECIFICITY OF ANTIGENS PREPARED BY COMBININGalpha- AND beta-GLUCOSIDES OF GLUCOSE WITH PROTEINS.

Authors:  O T Avery; W F Goebel; F H Babers
Journal:  J Exp Med       Date:  1932-04-30       Impact factor: 14.307

4.  ON THE SEROLOGICAL SPECIFICITY OF PEPTIDES. II.

Authors:  K Landsteiner; J van der Scheer
Journal:  J Exp Med       Date:  1934-05-31       Impact factor: 14.307

5.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : VI. THE SYNTHESIS OFp-AMINOPHENOLalpha-GLUCOSIDE AND ITS COUPLING WITH PROTEIN.

Authors:  W F Goebel; F H Babers; O T Avery
Journal:  J Exp Med       Date:  1932-04-30       Impact factor: 14.307

  5 in total
  10 in total

Review 1.  From glycophenotyping by (plant) lectin histochemistry to defining functionality of glycans by pairing with endogenous lectins.

Authors:  Herbert Kaltner; Gabriel García Caballero; Anna-Kristin Ludwig; Joachim C Manning; Hans-Joachim Gabius
Journal:  Histochem Cell Biol       Date:  2018-05-05       Impact factor: 4.304

2.  Effect of the nonreducing end of Shigella dysenteriae type 1 O-specific oligosaccharides on their immunogenicity as conjugates in mice.

Authors:  Vince Pozsgay; Joanna Kubler-Kielb; Rachel Schneerson; John B Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-28       Impact factor: 11.205

3.  Delayed hypersensitivity to hapten-protein conjugates. I. The effect of carrier protein and site of attachment to hapten.

Authors:  P G GELL; A M SILVERSTEIN
Journal:  J Exp Med       Date:  1962-05-01       Impact factor: 14.307

4.  A FURTHER STUDY OF THE CROSS REACTION BETWEEN THE SPECIFIC POLYSACCHARIDES OF TYPES III AND VIII PNEUMOCOCCI IN HORSE ANTISERA.

Authors:  M Heidelberger; E A Kabat; M Mayer
Journal:  J Exp Med       Date:  1942-01-01       Impact factor: 14.307

5.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : XII. THE IMMUNOLOGICAL PROPERTIES OF AN ARTIFICIAL ANTIGEN CONTAINING CELLOBIURONIC ACID.

Authors:  W F Goebel
Journal:  J Exp Med       Date:  1938-09-30       Impact factor: 14.307

6.  Studies on bacteriophage; the relationship between the somatic antigens of Shigella sonnei and their susceptibilitv to bacterial viruses.

Authors:  E M MILLER; W F GOEBEL
Journal:  J Exp Med       Date:  1949-09       Impact factor: 14.307

7.  The somatic antigen of a phage-resistant variant of Phase II Shigella sonnei.

Authors:  W F GEOBEL; M A JESAITIS
Journal:  J Exp Med       Date:  1952-11       Impact factor: 14.307

8.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : X. THE IMMUNOLOGICAL PROPERTIES OF AN ARTIFICIAL ANTIGEN CONTAINING GLUCURONIC ACID.

Authors:  W F Goebel
Journal:  J Exp Med       Date:  1936-06-30       Impact factor: 14.307

9.  ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS.

Authors:  K Landsteiner; J van der Scheer
Journal:  J Exp Med       Date:  1938-04-30       Impact factor: 14.307

10.  Binding properties of immunoglobulin combining sites specific for terminal or nonterminal antigenic determinants in dextran.

Authors:  J Cisar; E A Kabat; M M Dorner; J Liao
Journal:  J Exp Med       Date:  1975-08-01       Impact factor: 14.307

  10 in total

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