Literature DB >> 19861695

Midterm results of surgical treatment for adult osteochondritis dissecans of the knee.

Cecilia Pascual-Garrido1, Nicole A Friel, Spencer S Kirk, Allison G McNickle, Bernard R Bach, Charles A Bush-Joseph, Nikhil N Verma, Brian J Cole.   

Abstract

BACKGROUND: Determination of appropriate treatment options for adult osteochondritis dissecans is difficult, as most published papers on surgical osteochondritis dissecans treatment report outcomes in a population consisting of both adult and juvenile patients.
PURPOSE: This study examines the outcomes of surgical procedures in patients with adult osteochondritis dissecans. STUDY
DESIGN: Case series; Level of evidence, 4.
METHODS: The cohort included 46 adult patients (48 knees) with adult osteochondritis dissecans of the knee who had undergone surgical treatment (debridement, drilling, loose-body removal, arthroscopic reduction and internal fixation, microfracture, osteochondral allograft, or autologous chondrocyte implantation). The average patient age was 34 +/- 9.5 years (range, 20-49) and patients were followed for 4.0 +/- 1.8 years. The mean defect size was 4.5 +/- 2.7 cm(2). Outcomes were assessed via clinical assessment and established outcome scales, including the Lysholm, International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS), Tegner, Cincinnati, and Short Form-12.
RESULTS: Statistically significant improvement (P < .05) was noted in all outcome scales, including Noyes, Tegner, Lysholm, IKDC, KOOS (subdivided into 5 categories including Pain, Symptoms, Activities of Daily Living, Sport, and Quality of Life), Short Form-12 Physical, and Short Form-12 Mental. Seven knees (14%) had clinical failure of the initial treatment and underwent a revision procedure at a mean follow-up of 14 months. Patients treated with arthroscopic reduction and internal fixation and loose-body removal demonstrated a statistically higher postoperative percentage score increase for the KOOS Sport (P = .008) and KOOS Quality of Life (P = .03) categories than those treated with an osteochondral allograft.
CONCLUSION: Patients with adult osteochondritis dissecans of the knee, treated with surgical cartilage procedures, show durable function and symptomatic improvement at a mean 4.0 years of follow-up. Patients treated with arthroscopic reduction and internal fixation and loose-body removal demonstrated a greater improvement in outcome scores than those treated with osteochondral allograft.

Entities:  

Mesh:

Year:  2009        PMID: 19861695     DOI: 10.1177/0363546509350833

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  13 in total

Review 1.  Drilling juvenile osteochondritis dissecans: retro- or transarticular?

Authors:  Matthew J Gunton; James L Carey; Colin R Shaw; M Lucas Murnaghan
Journal:  Clin Orthop Relat Res       Date:  2013-04       Impact factor: 4.176

2.  Good clinical results but moderate osseointegration and defect filling of a cell-free multi-layered nano-composite scaffold for treatment of osteochondral lesions of the knee.

Authors:  Dominic T Mathis; Raphael Kaelin; Helmut Rasch; Markus P Arnold; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-07-15       Impact factor: 4.342

3.  Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population-based study in Olmsted County.

Authors:  A Pareek; T L Sanders; I T Wu; D R Larson; D B F Saris; A J Krych
Journal:  Osteoarthritis Cartilage       Date:  2017-07-12       Impact factor: 6.576

4.  Poor osteochondral repair by a biomimetic collagen scaffold: 1- to 3-year clinical and radiological follow-up.

Authors:  Bjørn Borsøe Christensen; Casper Bindzus Foldager; Jonas Jensen; Niels Christian Jensen; Martin Lind
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-18       Impact factor: 4.342

5.  Viability of loose body fragments in osteochondritis dissecans of the knee. A series of cases.

Authors:  Cecilia Pascual-Garrido; Ignacio Tanoira; Domingo L Muscolo; Miguel A Ayerza; Arturo Makino
Journal:  Int Orthop       Date:  2010-02-14       Impact factor: 3.075

6.  Arthroscopically assisted retrograde drilling for osteochondritis dissecans (OCD) lesions of the knee.

Authors:  Michael Hoffmann; Malte Schröder; Jan Philipp Petersen; Alexander Simon Spiro; Michael Kammal; Wolfgang Lehmann; Johannes Maria Rueger; Andreas Hermann Ruecker
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-01-19       Impact factor: 4.342

7.  Surgical management of osteochondritis dissecans of the knee.

Authors:  Brandon J Erickson; Peter N Chalmers; Adam B Yanke; Brian J Cole
Journal:  Curr Rev Musculoskelet Med       Date:  2013-06

8.  Surgical treatment for osteochondritis dessicans of the knee.

Authors:  Zachary Winthrop; Gregory Pinkowsky; William Hennrikus
Journal:  Curr Rev Musculoskelet Med       Date:  2015-12

9.  Treatment of a lateral tibial plateau osteochondritis dissecans lesion with subchondral injection of calcium phosphate.

Authors:  Geoffrey D Abrams; Eduard Alentorn-Geli; Joshua D Harris; Brian J Cole
Journal:  Arthrosc Tech       Date:  2013-07-19

10.  Treatment of severe osteochondral defects of the knee by combined autologous bone grafting and autologous chondrocyte implantation using fibrin gel.

Authors:  Yvonne E Könst; Rob J Benink; Ron Veldstra; Tjerk J van der Krieke; Marco N Helder; Barend J van Royen
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-11       Impact factor: 4.342

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.