A Pareek1, T L Sanders2, I T Wu3, D R Larson4, D B F Saris5, A J Krych6. 1. Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA. Electronic address: ayooshp@gmail.com. 2. Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA. Electronic address: sanders.thomas@mayo.edu. 3. Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA. Electronic address: wu.isabella@mayo.edu. 4. Health Sciences Research, Mayo Clinic, Rochester, MN, USA. Electronic address: larson.dirk@mayo.edu. 5. Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA; University of Twente, Enschede, The Netherlands; Department of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: saris.daniel@mayo.com. 6. Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA. Electronic address: krych.aaron@mayo.edu.
Abstract
OBJECTIVE: To (1) define population-based incidence of knee Osteochondritis dissecans (OCD) lesions using the population of Olmsted County, (2) examine trends over time, and (3) evaluate rate of surgical management over time. METHOD: Study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. Complete medical records were reviewed to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. RESULTS: Overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P < 0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11-15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11-15 years, OCD incidence increased significantly over the study period from 20.68 in 1976-1985 to 48.16 in 2006-2014 (per 100,000). CONCLUSIONS: Overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11-15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.
OBJECTIVE: To (1) define population-based incidence of knee Osteochondritis dissecans (OCD) lesions using the population of Olmsted County, (2) examine trends over time, and (3) evaluate rate of surgical management over time. METHOD: Study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. Complete medical records were reviewed to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. RESULTS: Overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P < 0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11-15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11-15 years, OCD incidence increased significantly over the study period from 20.68 in 1976-1985 to 48.16 in 2006-2014 (per 100,000). CONCLUSIONS: Overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11-15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.
Authors: Jennifer L St Sauver; Brandon R Grossardt; Barbara P Yawn; L Joseph Melton; Joshua J Pankratz; Scott M Brue; Walter A Rocca Journal: Int J Epidemiol Date: 2012-11-18 Impact factor: 7.196
Authors: Jennifer L St Sauver; Brandon R Grossardt; Barbara P Yawn; L Joseph Melton; Walter A Rocca Journal: Am J Epidemiol Date: 2011-03-23 Impact factor: 4.897
Authors: F Hefti; J Beguiristain; R Krauspe; B Möller-Madsen; V Riccio; C Tschauner; R Wetzel; R Zeller Journal: J Pediatr Orthop B Date: 1999-10 Impact factor: 1.041
Authors: Eric J Wall; Jason Vourazeris; Gregory D Myer; Kathleen H Emery; Jon G Divine; Todd G Nick; Timothy E Hewett Journal: J Bone Joint Surg Am Date: 2008-12 Impact factor: 5.284
Authors: Andrea Stracciolini; Rebecca Casciano; Hilary Levey Friedman; William P Meehan; Lyle J Micheli Journal: Am J Sports Med Date: 2013-06-05 Impact factor: 6.202
Authors: Štefan Zbýň; Cassiano Santiago; Casey P Johnson; Kai D Ludwig; Lin Zhang; Shelly Marette; Marc A Tompkins; Bradley J Nelson; Takashi Takahashi; Gregory J Metzger; Cathy S Carlson; Jutta M Ellermann Journal: J Orthop Res Date: 2021-10-20 Impact factor: 3.102
Authors: Abdul Wahed Kajabi; Štefan Zbýň; Casey P Johnson; Marc A Tompkins; Bradley J Nelson; Takashi Takahashi; Kevin G Shea; Shelly Marette; Cathy S Carlson; Jutta M Ellermann Journal: J Orthop Res Date: 2022-04-17 Impact factor: 3.102
Authors: Mario Hevesi; Thomas L Sanders; Ayoosh Pareek; Todd A Milbrandt; Bruce A Levy; Michael J Stuart; Daniel B F Saris; Aaron J Krych Journal: Cartilage Date: 2018-07-12 Impact factor: 4.634
Authors: Michael M Chau; Mikhail A Klimstra; Kelsey L Wise; Jutta M Ellermann; Ferenc Tóth; Cathy S Carlson; Bradley J Nelson; Marc A Tompkins Journal: J Bone Joint Surg Am Date: 2021-06-16 Impact factor: 6.558
Authors: Alexander Kolb; Simon Robinson; David Stelzeneder; Markus Schreiner; Catharina Chiari; Reinhard Windhager; Siegfried Trattnig; Klaus Bohndorf Journal: Eur Radiol Date: 2018-02-26 Impact factor: 5.315