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Literature DB >> 19828358

Design of membrane proteins: toward functional systems.

Abstract

Over the years, membrane-soluble peptides have provided a convenient model system to investigate the folding and assembly of integral membrane proteins. Recent advances in experimental and computational methods are now being translated into the design of functional membrane proteins. Applications include artificial modulators of membrane protein function, inhibitors of protein-protein interactions, and redox membrane proteins.

Mesh：

Substances：
Membrane Proteins

Year: 2009 PMID： 19828358 DOI： 10.1016/j.cbpa.2009.09.017

Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822

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Cited

14 in total

1. Modulation of function in a minimalist heme-binding membrane protein.

Authors: Sandip Shinde; Jeanine M Cordova; Brian W Woodrum; Giovanna Ghirlanda
Journal: J Biol Inorg Chem Date: 2012-02-04 Impact factor: 3.358

Review 2. Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport.

Authors: Nathan H Joh; Gevorg Grigoryan; Yibing Wu; William F DeGrado
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2017-08-05 Impact factor: 6.237

3. Naturally evolved G protein-coupled receptors adopt metastable conformations.

Authors: Kuang-Yui Michael Chen; Fuguo Zhou; Bartlomiej G Fryszczyn; Patrick Barth
Journal: Proc Natl Acad Sci U S A Date: 2012-07-30 Impact factor: 11.205

Review 4. Protein design: toward functional metalloenzymes.

Authors: Fangting Yu; Virginia M Cangelosi; Melissa L Zastrow; Matteo Tegoni; Jefferson S Plegaria; Alison G Tebo; Catherine S Mocny; Leela Ruckthong; Hira Qayyum; Vincent L Pecoraro
Journal: Chem Rev Date: 2014-03-24 Impact factor: 60.622

Review 5. Computational design of membrane proteins.

Authors: Jose Manuel Perez-Aguilar; Jeffery G Saven
Journal: Structure Date: 2012-01-11 Impact factor: 5.006

Review 6. Outer membrane protein design.

Authors: Joanna Sg Slusky
Journal: Curr Opin Struct Biol Date: 2016-11-26 Impact factor: 6.809

Design of membrane proteins: toward functional systems.

1. Modulation of function in a minimalist heme-binding membrane protein.

Review 2. Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport.

3. Naturally evolved G protein-coupled receptors adopt metastable conformations.

Review 4. Protein design: toward functional metalloenzymes.

Review 5. Computational design of membrane proteins.

Review 6. Outer membrane protein design.

7. The membrane- and soluble-protein helix-helix interactome: similar geometry via different interactions.

8. De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex.

Review 9. Recent advances in automated protein design and its future challenges.

10. Structural informatics, modeling, and design with an open-source Molecular Software Library (MSL).