Literature DB >> 19763861

A simple and rapid protocol for the synthesis of phenacyl derivatives using macroporous polymer-supported reagents.

Ali R Kiasat1, Soheil Sayyahi.   

Abstract

This article describes the use of Amberlite IRA-910 with different counter ions as excellent polymer-supported reagents in nucleophilic substitution reactions. The versatility of this protocol allowed the synthesis of a diversified library of phenacyl derivatives with high yields. The polymeric reagents can be reloaded several times with no loss of their efficiency.

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Year:  2009        PMID: 19763861     DOI: 10.1007/s11030-009-9191-3

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  13 in total

1.  Oxidizing Polymers: A Polymer-Supported, Recyclable Hypervalent Iodine(V) Reagent for the Efficient Conversion of Alcohols, Carbonyl Compounds, and Unsaturated Carbamates in Solution J.R. gratefully acknowledges generous support from Prof. M. E. Maier, Tübingen, the Strukturfonds of the University of Tübingen, the Fonds der Chemischen Industrie, and the DFG. We thank Graeme Nicholson, Dietmar Schmid, and Daniel Bischoff for analytical support.

Authors:  Gerhard Sorg; Anne Mengel; Günther Jung; Jörg Rademann
Journal:  Angew Chem Int Ed Engl       Date:  2001-12-03       Impact factor: 15.336

Review 2.  Reactions of solid-supported reagents and solid supports with alcohols and phenols through their hydroxyl functional group.

Authors:  Nguyen-Hai Nam; Soroush Sardari; Keykavous Parang
Journal:  J Comb Chem       Date:  2003 Sep-Oct

3.  Polymer-supported Mukaiyama reagent: a useful coupling reagent for the synthesis of esters and amides.

Authors:  Stefano Crosignani; Jerome Gonzalez; Dominique Swinnen
Journal:  Org Lett       Date:  2004-11-25       Impact factor: 6.005

4.  A new polymer-supported reagent for the synthesis of beta-lactams in solution.

Authors:  Donato Donati; Costanza Morelli; Andrea Porcheddu; Maurizio Taddei
Journal:  J Org Chem       Date:  2004-12-24       Impact factor: 4.354

5.  The structure of polymer-supported triphenylphosphine ditriflate: a potentially useful reagent in organic synthesis.

Authors:  Maria J Petersson; Ian D Jenkins; Wendy A Loughlin
Journal:  J Org Chem       Date:  2008-05-23       Impact factor: 4.354

6.  Functionalized Polymers-Emerging Versatile Tools for Solution-Phase Chemistry and Automated Parallel Synthesis.

Authors:  Andreas Kirschning; Holger Monenschein; Rüdiger Wittenberg
Journal:  Angew Chem Int Ed Engl       Date:  2001-02-16       Impact factor: 15.336

7.  Solid-phase synthesis of diaryl sulfides: direct coupling of solid-supported aryl halides with thiols using an insoluble polymer-supported reagent.

Authors:  Fabrice Gendre; Mathieu Yang; Philippe Diaz
Journal:  Org Lett       Date:  2005-06-23       Impact factor: 6.005

8.  Polymer-supported organotin reagents for regioselective halogenation of aromatic amines.

Authors:  Jean-Mathieu Chrétien; Françoise Zammattio; Erwan Le Grognec; Michaël Paris; Blanche Cahingt; Gilles Montavon; Jean-Paul Quintard
Journal:  J Org Chem       Date:  2005-04-01       Impact factor: 4.354

9.  Polymer-supported reagents for multi-step organic synthesis: application to the synthesis of sildenafil.

Authors:  I R Baxendale; S V Ley
Journal:  Bioorg Med Chem Lett       Date:  2000-09-04       Impact factor: 2.823

10.  Polymer resin library and the discovery of highly efficient polymer supported reagents and scavengers.

Authors:  Nicola Galaffu; Gianluca Sechi; Mark Bradley
Journal:  Mol Divers       Date:  2005       Impact factor: 2.943

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  2 in total

1.  A facile and one pot synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from terminal alkynes and phenacyl azides prepared from styrenes by CAN oxidant and sodium azide.

Authors:  Mosadegh Keshavarz; Rashid Badri
Journal:  Mol Divers       Date:  2011-07-29       Impact factor: 2.943

Review 2.  Synthetic Access to Aromatic α-Haloketones.

Authors:  Marre Porré; Gianmarco Pisanò; Fady Nahra; Catherine S J Cazin
Journal:  Molecules       Date:  2022-06-02       Impact factor: 4.927

  2 in total

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