Literature DB >> 19763860

Multicomponent reactions of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-nucleophiles: one-pot synthesis of 2H-pyridinyl-2-butenedioates in water.

Mohammad A Khalilzadeh1, Zinatossadat Hossaini, Samaneh Kharian.   

Abstract

An efficient synthesis of 2H-pyridinyl-2-butenedioate derivatives via reaction of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-nucleophiles in water as a solvent is described.

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Year:  2009        PMID： 19763860     DOI： 10.1007/s11030-009-9192-2

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  8 in total

Review 1.  Multi-component reactions and evolutionary chemistry.

Authors:  Lutz Weber
Journal:  Drug Discov Today       Date:  2002-01-15       Impact factor: 7.851

Review 2.  The application of multi-component reactions in drug discovery.

Authors:  Lutz Weber
Journal:  Curr Med Chem       Date:  2002-12       Impact factor: 4.530

3.  Multicomponent Reactions with Isocyanides.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-09-15       Impact factor: 15.336

4.  Three-component synthesis of functionalized 5-oxo-4,5-dihydroindeno[1,2-b]pyrans.

Authors:  Issa Yavari; Mehdi Sirouspour; Sanaz Souri
Journal:  Mol Divers       Date:  2006-06-16       Impact factor: 2.943

5.  Synthesis of functionalized 5-imino-2,5-dihydro-furans through the reaction of isocyanides with activated acetylenes in the presence of ethyl bromopyruvate.

Authors:  Issa Yavari; Zinatossadat Hossaini; Maryam Sabbaghan
Journal:  Mol Divers       Date:  2006-09-12       Impact factor: 2.943

6.  Novel applications of alkenyl zirconocenes.

Authors:  Peter Wipf; Christopher Kendall
Journal:  Chemistry       Date:  2002-04-15       Impact factor: 5.236

7.  Multicomponent coupling reactions for organic synthesis: chemoselective reactions with amide-aldehyde mixtures.

Authors:  Axel Jacobi von Wangelin; Helfried Neumann; Dirk Gördes; Stefan Klaus; Dirk Strübing; Matthias Beller
Journal:  Chemistry       Date:  2003-09-22       Impact factor: 5.236

8.  Reaction between alkyl isocyanides and isopropylidene Meldrum's acid in the presence of bidentate nucleophiles.

Authors:  Issa Yavari; Maryam Sabbaghan; Zinatossadat Hossaini
Journal:  Mol Divers       Date:  2006-11-23       Impact factor: 3.364
  8 in total

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