Literature DB >> 16779612

Three-component synthesis of functionalized 5-oxo-4,5-dihydroindeno[1,2-b]pyrans.

Issa Yavari1, Mehdi Sirouspour, Sanaz Souri.   

Abstract

Protonation of the reactive intermediates produced in the reaction between alkyl(aryl) isocyanides and dialkyl acetylenedicarboxylates by indan-1,3-dione leads to vinylnitrilium cations, which undergo carbon centered Michael type addition with the conjugate base of the CH-acid to produce functionalized 5-oxo-4,5-dihydroindeno[1,2-b]pyrans.

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Year:  2006        PMID： 16779612     DOI： 10.1007/s11030-006-9022-8

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  4 in total

1.  Multicomponent Reactions with Isocyanides.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-09-15       Impact factor: 15.336

Review 2.  Recent developments in isocyanide based multicomponent reactions in applied chemistry.

Authors:  Alexander Dömling
Journal:  Chem Rev       Date:  2006-01       Impact factor: 60.622

3.  Synthesis of benz[d]indeno[1,2-b]pyran-5,11-diones: versatile intermediates for the design and synthesis of topoisomerase I inhibitors.

Authors:  Andrew Morrell; Smitha Antony; Glenda Kohlhagen; Yves Pommier; Mark Cushman
Journal:  Bioorg Med Chem Lett       Date:  2006-01-25       Impact factor: 2.823

4.  Strategies for heterocyclic construction via novel multicomponent reactions based on isocyanides and nucleophilic carbenes.

Authors:  Vijay Nair; C Rajesh; A U Vinod; S Bindu; A R Sreekanth; J S Mathen; Lakshmi Balagopal
Journal:  Acc Chem Res       Date:  2003-12       Impact factor: 22.384
  4 in total
  6 in total

1.  Diastereoselective synthesis of fused [1,3]oxazines from ethyl pyruvate, activated acetylenes and N-heterocycles.

Authors:  Issa Yavari; Anvar Mirzaei; Zinatosadat Hossaini; Sanaz Souri
Journal:  Mol Divers       Date:  2009-07-04       Impact factor: 2.943

2.  A one-pot synthesis 3-alkoxycarbonyl-3,4-dihydro-2H-pyran-2-ones from vinylidene melderum's acids, dialkyl acetylenedicarboxylates, and simple alcohols.

Authors:  Samira Khandan; Issa Yavari; Javad Azizian
Journal:  Mol Divers       Date:  2022-03-10       Impact factor: 2.943

3.  Diastereoselective synthesis of fused [1,3]thiazolo[1,3]oxazins and [1,3]oxazino[2,3-b][1,3]benzothiazoles.

Authors:  Issa Yavari; Zinatossadat Hossaini; Sanaz Souri; Samereh Seyfi
Journal:  Mol Divers       Date:  2009-03-13       Impact factor: 2.943

4.  A synthesis of phosphorylated dioxohexahydropyrimidines from N,N'-dimethylurea, activated acetylenes, and trialkyl phosphites.

Authors:  Issa Yavari; Manijeh Nematpour; Zinatossadat Hossaini
Journal:  Mol Divers       Date:  2009-09-11       Impact factor: 2.943

5.  Multicomponent reactions of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-nucleophiles: one-pot synthesis of 2H-pyridinyl-2-butenedioates in water.

Authors:  Mohammad A Khalilzadeh; Zinatossadat Hossaini; Samaneh Kharian
Journal:  Mol Divers       Date:  2009-09-11       Impact factor: 2.943

6.  Synthesis of functionalized 1,2,4-triazole-3-thiones from ammonium isothiocyanate, acid chlorides, and arylhydrazines.

Authors:  Issa Yavari; Faezeh Shirgahi-Talari; Zinatossadat Hossaini; Maryam Sabbaghan; Samereh Seyfi
Journal:  Mol Divers       Date:  2010-01-16       Impact factor: 2.943
  6 in total

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