Literature DB >> 14502613

Multicomponent coupling reactions for organic synthesis: chemoselective reactions with amide-aldehyde mixtures.

Axel Jacobi von Wangelin1, Helfried Neumann, Dirk Gördes, Stefan Klaus, Dirk Strübing, Matthias Beller.   

Abstract

The acid-catalyzed condensation chemistry of simple amides and aldehydes provides a highly prolific source of diverse reactants for irreversible follow-up reactions. Amide-aldehyde mixtures have been successfully employed in multicomponent syntheses of N-acyl alpha-amino acids (via palladium-catalyzed amidocarbonylation) and various cyclohexene, cyclohexadiene, and benzene derivatives (via the amide-aldehyde-dienophile (AAD) reaction).

Entities:  

Year:  2003        PMID： 14502613     DOI： 10.1002/chem.200305048

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  11 in total

1.  New approach for the synthesis of novel acenaphtho[1,2-b]furan-8-amines.

Authors:  Reza Sandaroos; Saman Damavandi; Mehri Salimi; Ali Mohammadi; Azam Karimian; Maede Hasanpour
Journal:  Mol Divers       Date:  2012-01-25       Impact factor: 2.943

2.  Stereochemical control of the Passerini reaction.

Authors:  Peter R Andreana; Chang C Liu; Stuart L Schreiber
Journal:  Org Lett       Date:  2004-11-11       Impact factor: 6.005

3.  Microwave-assisted synthesis of a 3-aminoimidazo[1,2-a]-pyridine/pyrazine library by fluorous multicomponent reactions and subsequent cross-coupling reactions.

Authors:  Yimin Lu; Wei Zhang
Journal:  QSAR Comb Sci       Date:  2004

Review 4.  Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversification.

Authors:  James J Sahn; Brett A Granger; Stephen F Martin
Journal:  Org Biomol Chem       Date:  2014-08-19       Impact factor: 3.876

5.  A novel and facile synthesis of N-cyclohexyl-benzofurans by one-pot three-component reaction.

Authors:  Bita Baghernejad; Majid M Heravi; Hossein A Oskooie; Nargess Poormohammad; Maliheh Khorshidi; Yahia Sh Beheshtiha
Journal:  Mol Divers       Date:  2010-02-16       Impact factor: 2.943

6.  Strategies for innovation in multicomponent reaction design.

Authors:  Bruce Ganem
Journal:  Acc Chem Res       Date:  2009-03-17       Impact factor: 22.384

7.  A synthesis of phosphorylated dioxohexahydropyrimidines from N,N'-dimethylurea, activated acetylenes, and trialkyl phosphites.

Authors:  Issa Yavari; Manijeh Nematpour; Zinatossadat Hossaini
Journal:  Mol Divers       Date:  2009-09-11       Impact factor: 2.943

8.  Multicomponent reactions of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-nucleophiles: one-pot synthesis of 2H-pyridinyl-2-butenedioates in water.

Authors:  Mohammad A Khalilzadeh; Zinatossadat Hossaini; Samaneh Kharian
Journal:  Mol Divers       Date:  2009-09-11       Impact factor: 2.943

9.  Enantioselective Allylation of Alkenyl Boronates Promotes a 1,2-Metalate Rearrangement with 1,3-Diastereocontrol.

Authors:  Colton R Davis; Irungu K Luvaga; Joseph M Ready
Journal:  J Am Chem Soc       Date:  2021-03-23       Impact factor: 15.419

10.  A new paradigm for designing ring construction strategies for green organic synthesis: implications for the discovery of multicomponent reactions to build molecules containing a single ring.

Authors:  John Andraos
Journal:  Beilstein J Org Chem       Date:  2016-11-16       Impact factor: 2.883
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.