Literature DB >> 19662462

Megaprosthesis versus Condyle-sparing intercalary allograft: distal femoral sarcoma.

Melissa N Zimel1, Amy M Cizik, Timothy B Rapp, Jason S Weisstein, Ernest U Conrad.   

Abstract

UNLABELLED: Although functionally appealing in preserving the native knee, the condyle-sparing intercalary allograft of the distal femur may be associated with a higher risk of tumor recurrence and endoprosthetic replacement for malignant distal femoral bone tumors. We therefore compared the risk of local tumor recurrence between patients in these two types of reconstruction groups. We retrospectively reviewed 85 patients (mean age, 22 years; range, 4-82 years), 38 (45%) of whom had a condyle-sparing allograft and 47 (55%) of whom had endoprostheses. The minimum followup for both groups was 2 years (mean, 7 years; range, 2-19 years). Local recurrences occurred in 11% (five of 47) of the patients having implants versus 18% (seven of 38) of the patients having allografts. Using time to local recurrence as an end point, the Kaplan-Meier survivorship of the implant group was similar to that of the condyle-sparing allograft group at 2, 5, and 10 years (93% versus 87% at 2 years, 87% versus 81% at 5 years, and 87% versus 81% at 10 years, respectively). The condyle-sparing allograft procedure offers the potential advantage of retaining the native knee in a young patient population while incurring no greater risk of local recurrence as those offered the endoprosthetic procedure. LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

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Year:  2009        PMID: 19662462      PMCID: PMC2758955          DOI: 10.1007/s11999-009-1024-2

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  33 in total

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Review 7.  Osteosarcoma: a multidisciplinary approach to diagnosis and treatment.

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Review 8.  Limb-salvage surgery in the treatment of osteosarcoma in skeletally immature individuals.

Authors:  H A Finn; M A Simon
Journal:  Clin Orthop Relat Res       Date:  1991-01       Impact factor: 4.176

9.  Osteosarcoma in children: long-term functional analysis.

Authors:  Per-Ulf Tunn; Peter Schmidt-Peter; Doreen Pomraenke; Peter Hohenberger
Journal:  Clin Orthop Relat Res       Date:  2004-04       Impact factor: 4.176

10.  [Endoprosthesis management of the extremities of children after resection of primary malignant bone tumors].

Authors:  P Krepler; M Dominkus; C D Toma; R Kotz
Journal:  Orthopade       Date:  2003-11       Impact factor: 1.087

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  15 in total

1.  [Megaprostheses of the knee joint].

Authors:  K Anagnostakos; D Kohn
Journal:  Orthopade       Date:  2010-10       Impact factor: 1.087

Review 2.  Megaprosthesis versus Allograft Prosthesis Composite for massive skeletal defects.

Authors:  Deepak Gautam; Rajesh Malhotra
Journal:  J Clin Orthop Trauma       Date:  2017-09-25

3.  Computer-assisted surgical planning of complex bone tumor resections improves negative margin outcomes in a sawbones model.

Authors:  Amir Sternheim; Dani Rotman; Prakash Nayak; Michelle Arkhangorodsky; Michael J Daly; Jonathan C Irish; Peter C Ferguson; Jay S Wunder
Journal:  Int J Comput Assist Radiol Surg       Date:  2021-03-16       Impact factor: 2.924

Review 4.  Intercalary reconstructions after bone tumor resections: a review of treatments.

Authors:  Georgios N Panagopoulos; Andreas F Mavrogenis; Cyril Mauffrey; Jan Lesenský; Andrea Angelini; Panayiotis D Megaloikonomos; Vasilios G Igoumenou; John Papanastassiou; Olga Savvidou; Pietro Ruggieri; Panayiotis J Papagelopoulos
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5.  What are the Oncologic and Functional Outcomes After Joint Salvage Resections for Juxtaarticular Osteosarcoma About the Knee?

Authors:  Jing Li; Zhen Wang; Chuanlei Ji; Guojing Chen; Dong Liu; Haodong Zhu
Journal:  Clin Orthop Relat Res       Date:  2017-04-19       Impact factor: 4.176

6.  Revision Distal Femoral Arthroplasty With the Compress(®) Prosthesis Has a Low Rate of Mechanical Failure at 10 Years.

Authors:  Melissa N Zimel; German L Farfalli; Alexandra M Zindman; Elyn R Riedel; Carol D Morris; Patrick J Boland; John H Healey
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7.  Treatment of resistant nonunion of supracondylar fractures femur by megaprosthesis.

Authors:  Raju Vaishya; Ajay Pal Singh; Rohit Hasija; Arun Pal Singh
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-02-11       Impact factor: 4.342

8.  What Is the Outcome of Allograft and Intramedullary Free Fibula (Capanna Technique) in Pediatric and Adolescent Patients With Bone Tumors?

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Journal:  Clin Orthop Relat Res       Date:  2016-03       Impact factor: 4.176

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10.  Patella dislocation following distal femoral replacement after bone tumour resection.

Authors:  Toru Akiyama; Shotaro Kanda; Akinori Maeda; Minoru Endo; Kazuo Saita
Journal:  BMJ Case Rep       Date:  2014-07-29
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