Literature DB >> 14615851

[Endoprosthesis management of the extremities of children after resection of primary malignant bone tumors].

P Krepler1, M Dominkus, C D Toma, R Kotz.   

Abstract

In recent years, significant progress has been made in the treatment of primary malignant bone tumors. The surgeon is confronted with increasing demand for limb-sparing surgery by patients and parents alike. In the skeletally immature, resection of the growing physis will ultimately result in leg length discrepancies and functional impairment. An adequate reconstruction therefore calls for the compensation of the expected growth deficit to achieve symmetry and an optimized function of the extremity. Between 1975 and 2000, 55 patients (24 female, 31 male) were referred and treated at our institution. All patients were not older than 10 years (4.2-10, mean: 7.9 years). Histological diagnosis was Ewing's tumors ( n=19) and osteosarcoma ( n=36). Localization in the extremities was predominantly in the lower extremity with 63.6% around the knee joint (distal femur and proximal tibia). Surgical treatment was performed in all patients. Endoprosthetic reconstruction was performed in 34 patients (lower extremity n=30, 29 Howmedica Modular Reconstruction System, HMRS, 1 Pafford prosthesis; upper extremity n=4, 4 HMRS); in another case of humeral tumor involvement a resection replantation procedure was carried out. The other patients received a rotationplasty ( n=7), a biologic reconstruction ( n=6), resection replantation of the humerus ( n=1), no reconstruction ( n=3), or had to be amputated ( n=4). After a mean follow-up of 114 months (24-256 months) 11 patients had died. Even in young children endoprosthetic reconstruction with relatively early mobilization and high quality of life can be a very successful method for limb salvage. Optimal reconstructive results following resection of primary malignant bone tumors in children are reached when indications and limitations of each method are carefully considered on an individual basis taking into account the patients' expectations.

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Year:  2003        PMID: 14615851     DOI: 10.1007/s00132-003-0553-8

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  23 in total

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3.  Megaprostheses after resection of distal femoral tumors. A rotating hinge design in 30 patients followed for 2-7 years.

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Journal:  Acta Orthop Scand       Date:  1996-08

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Journal:  J Bone Joint Surg Br       Date:  1997-01

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Authors:  W F Enneking; D A Campanacci
Journal:  J Bone Joint Surg Am       Date:  2001-07       Impact factor: 5.284

Review 6.  Local control and survival from the Cooperative Osteosarcoma Study Group studies of the German Society of Pediatric Oncology and the Vienna Bone Tumor Registry.

Authors:  K Winkler; P Bieling; S Bielack; G Delling; C Dose; H Jürgens; R Kotz; J Ritter; M Salzer-Kuntschik
Journal:  Clin Orthop Relat Res       Date:  1991-09       Impact factor: 4.176

7.  Rotation-plasty for childhood osteosarcoma of the distal part of the femur.

Authors:  R Kotz; M Salzer
Journal:  J Bone Joint Surg Am       Date:  1982-09       Impact factor: 5.284

8.  Prosthetic and extremity survivorship after limb salvage for sarcoma. How long do the reconstructions last?

Authors:  S M Horowitz; D B Glasser; J M Lane; J H Healey
Journal:  Clin Orthop Relat Res       Date:  1993-08       Impact factor: 4.176

9.  Allograft arthrodesis treatment of bone tumors: a two-center study.

Authors:  D Donati; S Giacomini; E Gozzi; Y Salphale; M Mercuri; Henry J Mankin; Dempsy S Springfield; Mark C Gebhardt
Journal:  Clin Orthop Relat Res       Date:  2002-07       Impact factor: 4.176

10.  Extendable tumour endoprostheses for the leg in children.

Authors:  C Schiller; R Windhager; E J Fellinger; M Salzer-Kuntschik; A Kaider; R Kotz
Journal:  J Bone Joint Surg Br       Date:  1995-07
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  8 in total

1.  [Mega cups and partial pelvic replacement].

Authors:  R von Eisenhart-Rothe; H Gollwitzer; A Toepfer; H Pilge; B M Holzapfel; H Rechl; R Gradinger
Journal:  Orthopade       Date:  2010-10       Impact factor: 1.087

2.  Progress in musculoskeletal oncology from 1922 - 2012.

Authors:  Rainer I Kotz
Journal:  Int Orthop       Date:  2014-05       Impact factor: 3.075

3.  Megaprosthesis versus Condyle-sparing intercalary allograft: distal femoral sarcoma.

Authors:  Melissa N Zimel; Amy M Cizik; Timothy B Rapp; Jason S Weisstein; Ernest U Conrad
Journal:  Clin Orthop Relat Res       Date:  2009-08-07       Impact factor: 4.176

Review 4.  [Current results of tumour endoprosthetics in adolescents and adults].

Authors:  J Hardes; W Guder; M Dudda; M Nottrott; L-E Podleska; A Streitbürger
Journal:  Orthopade       Date:  2019-09       Impact factor: 1.087

5.  Analysis of limb function after various reconstruction methods according to tumor location following resection of pediatric malignant bone tumors.

Authors:  Yukihiro Yoshida; Shunzo Osaka; Yasuaki Tokuhashi
Journal:  World J Surg Oncol       Date:  2010-05-19       Impact factor: 2.754

Review 6.  Bone tumors in adolescents and young adults.

Authors:  Stefan S Bielack; Dorothe Carrle; Jendrik Hardes; Andreas Schuck; Michael Paulussen
Journal:  Curr Treat Options Oncol       Date:  2008-05-01

7.  A NEW APPROACH TO PARTIALKNEE ENDOPROSTHESIS IN PRIMARY BONE SARCOMAS.

Authors:  Valter Penna; Eduardo Areas Toller; Carla Pinheiro; Ricardo Gehrke Becker
Journal:  Rev Bras Ortop       Date:  2015-12-06

8.  The long-term outcomes following the use of inactivated autograft in the treatment of primary malignant musculoskeletal tumor.

Authors:  Jielai Yang; Bin Zhu; Kai Fu; Qingcheng Yang
Journal:  J Orthop Surg Res       Date:  2015-11-17       Impact factor: 2.359

  8 in total

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