Literature DB >> 10797332

Function and complications after ablative and limb-salvage therapy in lower extremity sarcoma of bone.

A J Renard1, R P Veth, H W Schreuder, C J van Loon, H S Koops, J R van Horn.   

Abstract

BACKGROUND AND OBJECTIVES: The functional results and the complications after several limb-saving and ablative treatments because of lower extremity bone sarcoma were evaluated.
METHODS: Seventy-seven surviving patients were evaluated according to the MSTS (American Musculoskeletal Tumor Society) functional rating system. Fifty-two patients had limb-saving and 25 had ablative therapy. Median follow-up was 97 months in the limb-saving group and 112 months in the ablative group.
RESULTS: Functional results in the limb-saving group were significantly better than in the ablative group (P = 0.0001). Functional results in patients with tumors about the knee joint were significantly better (P = 0.0064) after limb-saving surgery (i.e., endoprosthesis, knee arthrodesis, or rotationplasty) compared to functional results after ablative surgery (i.e., hip or knee disarticulation or above-the-knee amputation). Complications were 3 times more common after limb-salvage procedures and 4 times more common after endoprosthetic reconstructions compared to after ablative procedures. Complications after limb-saving therapy were fewest in tumors about the knee joint. In 3/28 patients, the endoprosthetic reconstruction had to be converted to an amputation.
CONCLUSIONS: Functional results were significantly better after limb-saving compared to after ablative therapy. Complications, however, were more common after limb-saving therapy.

Entities:  

Mesh:

Year:  2000        PMID: 10797332     DOI: 10.1002/(sici)1096-9098(200004)73:4<198::aid-jso3>3.0.co;2-x

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  34 in total

1.  Does limb-salvage surgery offer patients better quality of life and functional capacity than amputation?

Authors:  Farbod Malek; Jeremy S Somerson; Shannon Mitchel; Ronald P Williams
Journal:  Clin Orthop Relat Res       Date:  2012-07       Impact factor: 4.176

2.  Limb Salvage Versus Amputation in Conventional Appendicular Osteosarcoma: a Systematic Review.

Authors:  Julio J Jauregui; Vidushan Nadarajah; Joseph Munn; Robert Pivec; Bhaveen H Kapadia; Daniel M Lerman; Aditya V Maheshwari
Journal:  Indian J Surg Oncol       Date:  2018-01-20

3.  A new incision technique to reduce tibiofemoral mismatch in rotationplasty.

Authors:  Christian Ossendorf; Gerhard U Exner; Bruno Fuchs
Journal:  Clin Orthop Relat Res       Date:  2009-09-15       Impact factor: 4.176

4.  Follow-up of treated osteosarcoma patient.

Authors:  Gisele Eiras Martins; Stela Verzinhasse Perez
Journal:  Acta Ortop Bras       Date:  2012       Impact factor: 0.513

5.  The Pediatric Toronto Extremity Salvage Score (pTESS): Validation of a Self-reported Functional Outcomes Tool for Children with Extremity Tumors.

Authors:  Janine Piscione; Wendy Barden; Janie Barry; Alexandra Malkin; Trisha Roy; Tyki Sueyoshi; Karen Mazil; Steven Salomon; Firas Dandachli; Anthony Griffin; Hugo Saint-Yves; Pina Giuliano; Abha Gupta; Peter Ferguson; Katrin Scheinemann; Michelle Ghert; Robert E Turcotte; Lucie Lafay-Cousin; Joel Werier; Caron Strahlendorf; Marc Isler; Sophie Mottard; Samina Afzal; Megan E Anderson; Sevan Hopyan
Journal:  Clin Orthop Relat Res       Date:  2019-09       Impact factor: 4.176

Review 6.  [Risk factors and management strategies for early and late infections following reconstruction with special tumour endoprostheses].

Authors:  V Janz; J Löchel; A Trampuz; K-D Schaser; A Hofer; G I Wassilew
Journal:  Orthopade       Date:  2020-02       Impact factor: 1.087

7.  Poor long-term clinical results of saddle prosthesis after resection of periacetabular tumors.

Authors:  J A Jansen; M A J van de Sande; P D S Dijkstra
Journal:  Clin Orthop Relat Res       Date:  2012-10-05       Impact factor: 4.176

8.  Usefulness of limb salvage surgery for bone and soft tissue sarcomas of the distal lower leg.

Authors:  Rui Niimi; Akihiko Matsumine; Katsuyuki Kusuzaki; Shigeyuki Kuratsu; Nobuhito Araki; Yasuaki Aoki; Takafumi Ueda; Ikuo Kudawara; Akira Myoui; Makoto Ieguchi; Nobuyuki Hashimoto; Hideki Yoshikawa; Atsumasa Uchida
Journal:  J Cancer Res Clin Oncol       Date:  2008-04-02       Impact factor: 4.553

9.  Moving Forward Through Consensus: A Modified Delphi Approach to Determine the Top Research Priorities in Orthopaedic Oncology.

Authors:  Patricia Jacqueline Schneider; Nathan Evaniew; Paula McKay; Michelle Ghert
Journal:  Clin Orthop Relat Res       Date:  2017-08-30       Impact factor: 4.176

10.  Haptic robot-assisted surgery improves accuracy of wide resection of bone tumors: a pilot study.

Authors:  Fazel Khan; Andrew Pearle; Christopher Lightcap; Patrick J Boland; John H Healey
Journal:  Clin Orthop Relat Res       Date:  2013-03       Impact factor: 4.176

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