Literature DB >> 19637179

Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled.

Ho-Jin Lee1, Nick X Wang, De-Li Shi, Jie J Zheng.   

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Year:  2009        PMID： 19637179      PMCID： PMC2978498          DOI： 10.1002/anie.200902981

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  52 in total

1.  PRODRG: a tool for high-throughput crystallography of protein-ligand complexes.

Authors:  Alexander W Schüttelkopf; Daan M F van Aalten
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2004-07-21

2.  A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus.

Authors:  M Brannon; M Gomperts; L Sumoy; R T Moon; D Kimelman
Journal:  Genes Dev       Date:  1997-09-15       Impact factor: 11.361

3.  Improved NMR spectra of a protein-DNA complex through rational mutagenesis and the application of a sensitivity optimized isotope-filtered NOESY experiment.

Authors:  J Iwahara; J M Wojciak; R T Clubb
Journal:  J Biomol NMR       Date:  2001-03       Impact factor: 2.835

4.  Sulindac suppresses beta-catenin expression in human cancer cells.

Authors:  Anjia Han; Zibo Song; Chang Tong; Dong Hu; Xiuli Bi; Leonard H Augenlicht; Wancai Yang
Journal:  Eur J Pharmacol       Date:  2008-02-05       Impact factor: 4.432

5.  Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled.

Authors:  David Grandy; Jufang Shan; Xinxin Zhang; Sujata Rao; Shailaja Akunuru; Hongyan Li; Yanhui Zhang; Ivan Alpatov; Xin A Zhang; Richard A Lang; De-Li Shi; Jie J Zheng
Journal:  J Biol Chem       Date:  2009-04-21       Impact factor: 5.157

6.  DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

Authors:  Xia Jiang; Jing Tan; Jingsong Li; Saul Kivimäe; Xiaojing Yang; Li Zhuang; Puay Leng Lee; Mark T W Chan; Lawrence W Stanton; Edison T Liu; Benjamin N R Cheyette; Qiang Yu
Journal:  Cancer Cell       Date:  2008-06       Impact factor: 31.743

Review 7.  WNT and beta-catenin signalling: diseases and therapies.

Authors:  Randall T Moon; Aimee D Kohn; Giancarlo V De Ferrari; Ajamete Kaykas
Journal:  Nat Rev Genet       Date:  2004-09       Impact factor: 53.242

8.  Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.

Authors:  Weijun Pan; Sun-Cheol Choi; He Wang; Yuanbo Qin; Laura Volpicelli-Daley; Laura Swan; Louise Lucast; Cynthia Khoo; Xiaowu Zhang; Lin Li; Charles S Abrams; Sergei Y Sokol; Dianqing Wu
Journal:  Science       Date:  2008-09-05       Impact factor: 47.728

9.  PDZ7 of glutamate receptor interacting protein binds to its target via a novel hydrophobic surface area.

Authors:  Wei Feng; Jing-Song Fan; Ming Jiang; Ya-Wei Shi; Mingjie Zhang
Journal:  J Biol Chem       Date:  2002-08-23       Impact factor: 5.157

10.  Reorganisation of Wnt-response pathways in colorectal tumorigenesis.

Authors:  G M Caldwell; C E Jones; Y Soon; R Warrack; D G Morton; G M Matthews
Journal:  Br J Cancer       Date:  2008-04-15       Impact factor: 7.640
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  41 in total

1.  Discovery of a small-molecule inhibitor of Dvl-CXXC5 interaction by computational approaches.

Authors:  Songling Ma; Jiwon Choi; Xuemei Jin; Hyun-Yi Kim; Ji-Hye Yun; Weontae Lee; Kang-Yell Choi; Kyoung Tai No
Journal:  J Comput Aided Mol Des       Date:  2018-04-07       Impact factor: 3.686

2.  Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein.

Authors:  Ho-Jin Lee; David Finkelstein; Xiaofeng Li; Dianqing Wu; De-Li Shi; Jie J Zheng
Journal:  J Biol Chem       Date:  2010-11-02       Impact factor: 5.157

Review 3.  Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition.

Authors:  Xu Liu; Ernesto J Fuentes
Journal:  Int Rev Cell Mol Biol       Date:  2018-06-28       Impact factor: 6.813

Review 4.  Modulating the wnt signaling pathway with small molecules.

Authors:  Freddi Huan Tran; Jie J Zheng
Journal:  Protein Sci       Date:  2017-02-11       Impact factor: 6.725

5.  Downregulating the canonical Wnt/β-catenin signaling pathway attenuates the susceptibility to autism-like phenotypes by decreasing oxidative stress.

Authors:  Yinghua Zhang; Yan Sun; Fei Wang; Zhongping Wang; Yuwen Peng; Ruixi Li
Journal:  Neurochem Res       Date:  2012-02-29       Impact factor: 3.996

6.  Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand.

Authors:  Graham T Holt; Jonathan D Jou; Nicholas P Gill; Anna U Lowegard; Jeffrey W Martin; Dean R Madden; Bruce R Donald
Journal:  J Phys Chem B       Date:  2019-11-27       Impact factor: 2.991

Review 7.  Pharmacologic Manipulation of Wnt Signaling and Cancer Stem Cells.

Authors:  Yann Duchartre; Yong-Mi Kim; Michael Kahn
Journal:  Methods Mol Biol       Date:  2017

Review 8.  Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update.

Authors:  Naoko Takebe; Lucio Miele; Pamela Jo Harris; Woondong Jeong; Hideaki Bando; Michael Kahn; Sherry X Yang; S Percy Ivy
Journal:  Nat Rev Clin Oncol       Date:  2015-04-07       Impact factor: 66.675

9.  Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.

Authors:  Jeanine F Amacher; Patrick R Cushing; Christopher D Bahl; Tobias Beck; Dean R Madden
Journal:  J Biol Chem       Date:  2012-12-15       Impact factor: 5.157

10.  PDZ domains and their binding partners: structure, specificity, and modification.

Authors:  Ho-Jin Lee; Jie J Zheng
Journal:  Cell Commun Signal       Date:  2010-05-28       Impact factor: 5.712
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