| Literature DB >> 19546925 |
A E Desjardins1, B J Vakoc, W Y Oh, S M Motaghiannezam, G J Tearney, B E Bouma.
Abstract
We present a novel method for rapidly acquiring optical coherence tomography (OCT) images at multiple backscattering angles. By angularly compounding these images, high levels of speckle reduction were achieved. Signal-to-noise ratio (SNR) improvements of 3.4 dB were obtained from a homogeneous tissue phantom, which was in good agreement with the predictions of a statistical model of speckle that incorporated the optical parameters of the imaging system. In addition, the fast acquisition rate of the system (10 kHz A-line repetition rate) allowed angular compounding to be performed in vivo without significant motion artifacts. Speckle-reduced OCT images of human dermis show greatly improved delineation of tissue microstructure.Entities:
Year: 2007 PMID: 19546925 PMCID: PMC2704484 DOI: 10.1364/oe.15.006200
Source DB: PubMed Journal: Opt Express ISSN: 1094-4087 Impact factor: 3.894