INTRODUCTION AND HYPOTHESIS: The aim of this study is to compare acellular dermal matrix to standard colporrhaphy for cystocele repair. METHODS: One hundred two patients with greater than or equal to stage II anterior prolapse (Aa or Ba 0) who underwent anterior colporrhaphy with acellular dermal implant attached to the arcus between October 2003 and February 2007 were compared to 89 controls who received standard anterior colporrhaphy. Objective recurrence was defined as greater than or equal to stage II (Aa or Ba -1). RESULTS: The dermal graft and colporrhaphy groups were comparable in age, parity, body mass index, and concomitant surgeries except hysteropexy and hysterectomy. Regression was performed for possible confounders. Postoperatively, 14 (19%) recurrences were identified in the dermal graft group vs. 26 (43%) in the colporrhaphy group (p = 0.004). Two patients underwent reoperations for cystocele recurrence in the study group vs. four in the control group. Time to normal voiding, subjective stress urinary incontinence, estimated blood loss, and length of hospital stay did not differ between groups. CONCLUSION: Dermal acellular matrix provides benefit over standard colporrhaphy.
INTRODUCTION AND HYPOTHESIS: The aim of this study is to compare acellular dermal matrix to standard colporrhaphy for cystocele repair. METHODS: One hundred two patients with greater than or equal to stage II anterior prolapse (Aa or Ba 0) who underwent anterior colporrhaphy with acellular dermal implant attached to the arcus between October 2003 and February 2007 were compared to 89 controls who received standard anterior colporrhaphy. Objective recurrence was defined as greater than or equal to stage II (Aa or Ba -1). RESULTS: The dermal graft and colporrhaphy groups were comparable in age, parity, body mass index, and concomitant surgeries except hysteropexy and hysterectomy. Regression was performed for possible confounders. Postoperatively, 14 (19%) recurrences were identified in the dermal graft group vs. 26 (43%) in the colporrhaphy group (p = 0.004). Two patients underwent reoperations for cystocele recurrence in the study group vs. four in the control group. Time to normal voiding, subjective stress urinary incontinence, estimated blood loss, and length of hospital stay did not differ between groups. CONCLUSION: Dermal acellular matrix provides benefit over standard colporrhaphy.
Authors: P K Sand; S Koduri; R W Lobel; H A Winkler; J Tomezsko; P J Culligan; R Goldberg Journal: Am J Obstet Gynecol Date: 2001-06 Impact factor: 8.661
Authors: Antonio Espinosa-de-los-Monteros; Jorge I de la Torre; Ian Marrero; Patricio Andrades; Michael R Davis; Luis O Vásconez Journal: Ann Plast Surg Date: 2007-03 Impact factor: 1.539
Authors: Manhan K Vu; Juraj Letko; Kelly Jirschele; Adam Gafni-Kane; Aimee Nguyen; Honyan Du; Roger P Goldberg Journal: Int Urogynecol J Date: 2012-04-25 Impact factor: 2.894