Literature DB >> 19476377

DNA topoisomerase I inhibitors: chemistry, biology, and interfacial inhibition.

Yves Pommier1.   

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Year:  2009        PMID： 19476377      PMCID： PMC2707511          DOI： 10.1021/cr900097c

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  134 in total

1.  The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs.

Authors:  A Kathleen McClendon; Neil Osheroff
Journal:  Biochemistry       Date:  2006-03-07       Impact factor: 3.162

2.  Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.

Authors:  Smitha Antony; Keli K Agama; Ze-Hong Miao; Melinda Hollingshead; Susan L Holbeck; Mollie H Wright; Lyuba Varticovski; Muthukaman Nagarajan; Andrew Morrell; Mark Cushman; Yves Pommier
Journal:  Mol Pharmacol       Date:  2006-06-23       Impact factor: 4.436

3.  Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae.

Authors:  Changchun Deng; James A Brown; Dongqing You; J Martin Brown
Journal:  Genetics       Date:  2005-04-16       Impact factor: 4.562

4.  Synthesis and evaluation of indenoisoquinoline topoisomerase I inhibitors substituted with nitrogen heterocycles.

Authors:  Muthukaman Nagarajan; Andrew Morrell; Alexandra Ioanoviciu; Smitha Antony; Glenda Kohlhagen; Keli Agama; Melinda Hollingshead; Yves Pommier; Mark Cushman
Journal:  J Med Chem       Date:  2006-10-19       Impact factor: 7.446

5.  Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings.

Authors:  Muthukaman Nagarajan; Andrew Morrell; Brian C Fort; Marintha Rae Meckley; Smitha Antony; Glenda Kohlhagen; Yves Pommier; Mark Cushman
Journal:  J Med Chem       Date:  2004-11-04       Impact factor: 7.446

6.  Dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines.

Authors:  Xiangshu Xiao; Ze-Hong Miao; Smitha Antony; Yves Pommier; Mark Cushman
Journal:  Bioorg Med Chem Lett       Date:  2005-06-02       Impact factor: 2.823

7.  Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.

Authors:  Andrew Morrell; Smitha Antony; Glenda Kohlhagen; Yves Pommier; Mark Cushman
Journal:  Bioorg Med Chem Lett       Date:  2004-07-16       Impact factor: 2.823

8.  Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.

Authors:  Michael S Braun; Susan D Richman; Philip Quirke; Catherine Daly; Julian W Adlard; Faye Elliott; Jennifer H Barrett; Peter Selby; Angela M Meade; Richard J Stephens; Mahesh K B Parmar; Matthew T Seymour
Journal:  J Clin Oncol       Date:  2008-06-01       Impact factor: 44.544

9.  Protein-linked DNA strand breaks induced by NSC 314622, a novel noncamptothecin topoisomerase I poison.

Authors:  G Kohlhagen; K D Paull; M Cushman; P Nagafuji; Y Pommier
Journal:  Mol Pharmacol       Date:  1998-07       Impact factor: 4.436

10.  Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity.

Authors:  Thomas D Pfister; William C Reinhold; Keli Agama; Shalu Gupta; Sonny A Khin; Robert J Kinders; Ralph E Parchment; Joseph E Tomaszewski; James H Doroshow; Yves Pommier
Journal:  Mol Cancer Ther       Date:  2009-07-07       Impact factor: 6.261
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  176 in total

1.  Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282.

Authors:  Dhriti Sooryakumar; Thomas S Dexheimer; Beverly A Teicher; Yves Pommier
Journal:  Mol Cancer Ther       Date:  2011-06-02       Impact factor: 6.261

Review 2.  DNA topoisomerases and their poisoning by anticancer and antibacterial drugs.

Authors:  Yves Pommier; Elisabetta Leo; HongLiang Zhang; Christophe Marchand
Journal:  Chem Biol       Date:  2010-05-28

3.  T7 RNA polymerases backed up by covalently trapped proteins catalyze highly error prone transcription.

Authors:  Toshiaki Nakano; Ryo Ouchi; Junya Kawazoe; Seung Pil Pack; Keisuke Makino; Hiroshi Ide
Journal:  J Biol Chem       Date:  2012-01-10       Impact factor: 5.157

4.  Combination of HDAC and topoisomerase inhibitors in small cell lung cancer.

Authors:  Jhanelle Gray; Christopher L Cubitt; Shumin Zhang; Alberto Chiappori
Journal:  Cancer Biol Ther       Date:  2012-06-01       Impact factor: 4.742

Review 5.  Mitochondrial DNA damage and its consequences for mitochondrial gene expression.

Authors:  Susan D Cline
Journal:  Biochim Biophys Acta       Date:  2012-06-19

6.  Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.

Authors:  Yeonee Seol; Hongliang Zhang; Keli Agama; Nicholas Lorence; Yves Pommier; Keir C Neuman
Journal:  Mol Cancer Ther       Date:  2015-09-08       Impact factor: 6.261

7.  Protein kinase CK2 is a central regulator of topoisomerase I hyperphosphorylation and camptothecin sensitivity in cancer cell lines.

Authors:  Keya Bandyopadhyay; Ruth A Gjerset
Journal:  Biochemistry       Date:  2011-01-12       Impact factor: 3.162

8.  ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage.

Authors:  Jee-In Heo; Soo-Jin Oh; Yoon-Jung Kho; Jeong-Hyeon Kim; Hong-Joon Kang; Seong-Hoon Park; Hyun-Seok Kim; Jong-Yeon Shin; Min-Ju Kim; Minju Kim; Sung Chan Kim; Jae-Bong Park; Jaebong Kim; Jae-Yong Lee
Journal:  Mol Biol Rep       Date:  2012-05-11       Impact factor: 2.316

9.  Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.

Authors:  Yonghwan Kim; Gabriella S Spitz; Uma Veturi; Francis P Lach; Arleen D Auerbach; Agata Smogorzewska
Journal:  Blood       Date:  2012-10-23       Impact factor: 22.113

Review 10.  Drugging topoisomerases: lessons and challenges.

Authors:  Yves Pommier
Journal:  ACS Chem Biol       Date:  2013-01-04       Impact factor: 5.100
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