| Literature DB >> 19467352 |
Abstract
The concept of reserve has been proposed to account for the disjunction between the degree of brain damage and its clinical outcome. This paper attempts to produce a coherent theoretical account the reserve in general and of cognitive reserve in particular. It reviews epidemiologic data supporting the concept of cognitive reserve, with a particular focus of its implications for aging and dementia. It then focuses on methodologic issues that are important when attempting to elucidate the neural underpinnings of cognitive reserve using imaging studies, and reviews some of our group's work in order to demonstrate these issues.Entities:
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Year: 2009 PMID: 19467352 PMCID: PMC2739591 DOI: 10.1016/j.neuropsychologia.2009.03.004
Source DB: PubMed Journal: Neuropsychologia ISSN: 0028-3932 Impact factor: 3.139