Literature DB >> 19431180

Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe.

Yi Xiao1, Kory J I Plakos, Xinhui Lou, Ryan J White, Jiangrong Qian, Kevin W Plaxco, H Tom Soh.   

Abstract

Singled out for its singularity: In a single-step, single-component, fluorescence-based method for the detection of single-nucleotide polymorphisms at room temperature, the sensor is comprised of a single, self-complementary DNA strand that forms a triple-stem structure. The large conformational change that occurs upon binding to perfectly matched (PM) targets results in a significant increase in fluorescence (see picture; F = fluorophore, Q = quencher).

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Year:  2009        PMID： 19431180      PMCID： PMC3053031          DOI： 10.1002/anie.200900369

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  45 in total

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2.  Nonenzymatic autoligation in direct three-color detection of RNA and DNA point mutations.

Authors:  Y Xu; N B Karalkar; E T Kool
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3.  A binary DNA probe for highly specific nucleic Acid recognition.

Authors:  Dmitry M Kolpashchikov
Journal:  J Am Chem Soc       Date:  2006-08-16       Impact factor: 15.419

4.  Inorganic-organic hybrid luminescent binary probe for DNA detection based on spin-forbidden resonance energy transfer.

Authors:  Angel A Martí; Cindy A Puckett; Joanne Dyer; Nathan Stevens; Steffen Jockusch; Jingyue Ju; Jacqueline K Barton; Nicholas J Turro
Journal:  J Am Chem Soc       Date:  2007-06-26       Impact factor: 15.419

5.  Split DNA enzyme for visual single nucleotide polymorphism typing.

Authors:  Dmitry M Kolpashchikov
Journal:  J Am Chem Soc       Date:  2008-02-19       Impact factor: 15.419

6.  KnotSeeker: heuristic pseudoknot detection in long RNA sequences.

Authors:  Jana Sperschneider; Amitava Datta
Journal:  RNA       Date:  2008-02-26       Impact factor: 4.942

7.  Low-noise stemless PNA beacons for sensitive DNA and RNA detection.

Authors:  Elke Socher; Lucas Bethge; Andrea Knoll; Nadine Jungnick; Andreas Herrmann; Oliver Seitz
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

8.  Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays.

Authors:  J B Fan; X Chen; M K Halushka; A Berno; X Huang; T Ryder; R J Lipshutz; D J Lockhart; A Chakravarti
Journal:  Genome Res       Date:  2000-06       Impact factor: 9.043

9.  FIT probes: peptide nucleic acid probes with a fluorescent base surrogate enable real-time DNA quantification and single nucleotide polymorphism discovery.

Authors:  Elke Socher; Dilip V Jarikote; Andrea Knoll; Lars Röglin; Jens Burmeister; Oliver Seitz
Journal:  Anal Biochem       Date:  2008-01-12       Impact factor: 3.365

10.  A reliable general purpose method for extracting genomic DNA from Dictyostelium cells.

Authors:  Karen E Pilcher; Petra Fey; Pascale Gaudet; Anthony S Kowal; Rex L Chisholm
Journal:  Nat Protoc       Date:  2007       Impact factor: 13.491
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  24 in total

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Authors:  Hsin-Chih Yeh; Jaswinder Sharma; Ie-Ming Shih; Dung M Vu; Jennifer S Martinez; James H Werner
Journal:  J Am Chem Soc       Date:  2012-07-10       Impact factor: 15.419

2.  Spectra, Stability and Labeling of a Novel Carbazole Derivative as a Fluorescent Turn-on DNA Probe.

Authors:  Xuening Fei; Ran Li; Dayong Lin; Yingchun Gu; Lu Yu
Journal:  J Fluoresc       Date:  2015-07-16       Impact factor: 2.217

3.  Highly specific SNP detection using 2D graphene electronics and DNA strand displacement.

Authors:  Michael T Hwang; Preston B Landon; Joon Lee; Duyoung Choi; Alexander H Mo; Gennadi Glinsky; Ratnesh Lal
Journal:  Proc Natl Acad Sci U S A       Date:  2016-06-13       Impact factor: 11.205

4.  An exonuclease III and graphene oxide-aided assay for DNA detection.

Authors:  Lu Peng; Zhi Zhu; Yan Chen; Da Han; Weihong Tan
Journal:  Biosens Bioelectron       Date:  2012-03-10       Impact factor: 10.618

5.  Using commercially available personal glucose meters for portable quantification of DNA.

Authors:  Yu Xiang; Yi Lu
Journal:  Anal Chem       Date:  2012-02-06       Impact factor: 6.986

6.  A branch-migration based fluorescent probe for straightforward, sensitive and specific discrimination of DNA mutations.

Authors:  Xianjin Xiao; Tongbo Wu; Lei Xu; Wei Chen; Meiping Zhao
Journal:  Nucleic Acids Res       Date:  2017-06-02       Impact factor: 16.971

7.  Optimizing the specificity of nucleic acid hybridization.

Authors:  David Yu Zhang; Sherry Xi Chen; Peng Yin
Journal:  Nat Chem       Date:  2012-01-22       Impact factor: 24.427

8.  Rapid genotyping using pyrene-perylene locked nucleic acid complexes.

Authors:  T Santhosh Kumar; Anna Myznikova; Evgeniya Samokhina; Irina Kira Astakhova
Journal:  Artif DNA PNA XNA       Date:  2013 Apr-Jun

9.  Conditionally fluorescent molecular probes for detecting single base changes in double-stranded DNA.

Authors:  Sherry Xi Chen; David Yu Zhang; Georg Seelig
Journal:  Nat Chem       Date:  2013-07-28       Impact factor: 24.427

10.  An electrochemical sensor for single nucleotide polymorphism detection in serum based on a triple-stem DNA probe.

Authors:  Yi Xiao; Xinhui Lou; Takanori Uzawa; Kory J I Plakos; Kevin W Plaxco; H Tom Soh
Journal:  J Am Chem Soc       Date:  2009-10-28       Impact factor: 15.419
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