Literature DB >> 19377989

In vitro selection of protein and peptide libraries using mRNA display.

Terry T Takahashi1, Richard W Roberts.   

Abstract

In vitro genetic approaches are powerful solutions to the protein design problem. mRNA display is an in vitro selection technique enabling the design of peptide and protein ligands ranging from one to over 100 amino acids. Libraries containing more than 10 trillion unique sequences can be synthesized and sieved with exquisite control over binding stringency and specificity.

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Year:  2009        PMID: 19377989     DOI: 10.1007/978-1-59745-557-2_17

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  13 in total

1.  mRNA Display Discovery of a Novel Programmed Death Ligand 1 (PD-L1) Binding Peptide (a Peptide Ligand for PD-L1).

Authors:  Golnaz Kamalinia; Brian J Engel; Anupallavi Srinivasamani; Brian J Grindel; Justin N Ong; Michael A Curran; Terry T Takahashi; Steven W Millward; Richard W Roberts
Journal:  ACS Chem Biol       Date:  2020-04-30       Impact factor: 5.100

2.  Rapid mRNA-display selection of an IL-6 inhibitor using continuous-flow magnetic separation.

Authors:  C Anders Olson; Jonathan D Adams; Terry T Takahashi; Hangfei Qi; Shannon M Howell; Ting-Ting Wu; Richard W Roberts; Ren Sun; H Tom Soh
Journal:  Angew Chem Int Ed Engl       Date:  2011-07-14       Impact factor: 15.336

3.  Overview of cell-free protein synthesis: historic landmarks, commercial systems, and expanding applications.

Authors:  Shaorong Chong
Journal:  Curr Protoc Mol Biol       Date:  2014-10-01

4.  In vitro evolution of enzymes.

Authors:  Misha V Golynskiy; John C Haugner; Aleardo Morelli; Dana Morrone; Burckhard Seelig
Journal:  Methods Mol Biol       Date:  2013

5.  Single-round, multiplexed antibody mimetic design through mRNA display.

Authors:  C Anders Olson; Jeff Nie; Jonathan Diep; Ibrahim Al-Shyoukh; Terry T Takahashi; Laith Q Al-Mawsawi; Jennifer M Bolin; Angela L Elwell; Scott Swanson; Ron Stewart; James A Thomson; H Tom Soh; Richard W Roberts; Ren Sun
Journal:  Angew Chem Int Ed Engl       Date:  2012-11-04       Impact factor: 15.336

6.  Discs large 1 controls daughter-cell polarity after cytokinesis in vertebrate morphogenesis.

Authors:  Yuwei Li; Jason A Junge; Cosimo Arnesano; Garrett G Gross; Jeffrey H Miner; Rex Moats; Richard W Roberts; Don B Arnold; Scott E Fraser
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-30       Impact factor: 11.205

7.  A highly scalable peptide-based assay system for proteomics.

Authors:  Igor A Kozlov; Elliot R Thomsen; Sarah E Munchel; Patricia Villegas; Petr Capek; Austin J Gower; Stephanie J K Pond; Eugene Chudin; Mark S Chee
Journal:  PLoS One       Date:  2012-06-12       Impact factor: 3.240

Review 8.  Directing evolution of novel ligands by mRNA display.

Authors:  Golnaz Kamalinia; Brian J Grindel; Terry T Takahashi; Steven W Millward; Richard W Roberts
Journal:  Chem Soc Rev       Date:  2021-06-24       Impact factor: 60.615

9.  Reverse Engineering of Vaccine Antigens Using High Throughput Sequencing-enhanced mRNA Display.

Authors:  Nini Guo; Hongying Duan; Alla Kachko; Benjamin W Krause; Marian E Major; Philip R Krause
Journal:  EBioMedicine       Date:  2015-06-30       Impact factor: 8.143

Review 10.  Strategies towards Targeting Gαi/s Proteins: Scanning of Protein-Protein Interaction Sites To Overcome Inaccessibility.

Authors:  Britta Nubbemeyer; Anna Pepanian; Ajay Abisheck Paul George; Diana Imhof
Journal:  ChemMedChem       Date:  2021-03-22       Impact factor: 3.466

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