| Literature DB >> 19364874 |
Rabih O Darouiche1, Mohammad D Mansouri, Marlowe J Schneidkraut.
Abstract
Telavancin is an investigational lipoglycopeptide antibiotic that is active against gram-positive pathogens. In an in vivo rabbit model, subtherapeutic (15-mg/kg) and therapeutic (30- or 45-mg/kg) doses of telavancin were demonstrated to be noninferior and superior to vancomycin (20 mg/kg), respectively, for preventing subcutaneous implant colonization and infection by Staphylococcus aureus.Entities:
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Year: 2009 PMID: 19364874 PMCID: PMC2687217 DOI: 10.1128/AAC.01101-08
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191