Literature DB >> 19326398

Student t-tests for potentially abnormal data.

Jonathan J Shuster1.   

Abstract

When the one-sample or two-sample t-test is either taught in the class room or applied in practice to small samples, there is considerable divergence of opinion as to whether or not the inferences drawn are valid. Many point to the 'Robustness' of the t-test to violations of assumptions, while others use rank or other robust methods because they believe that the t-test is not robust against violations of such assumptions. It is quite likely, despite the apparent divergence of these two opinions, that both arguments have considerable merit. If we agree that this question cannot possibly be resolved in general, the issue becomes one of determining, before any actual data have been collected, whether the t-test will or will not be robust in a specific application. This paper describes statistical analysis system software, covering a large collection of potential input probability distributions, to investigate both the null and power properties of various one- and two-sample t-tests and their normal approximations, as well as the Wilcoxon two-sample and sign-rank one-sample tests, allowing potential practitioners to determine, at the study design stage, whether the t-test will be robust in their specific application. Sample size projections, based on these actual distributions, are also included. This paper is not intended as a tool to assess robustness after the data have been collected.

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Year:  2009        PMID: 19326398      PMCID: PMC3666168          DOI: 10.1002/sim.3581

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  7 in total

1.  Robustness of the t test applied to data distorted from normality by floor effects.

Authors:  L M Sullivan; R B D'Agostino
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2.  Diagnostics for assumptions in moderate to large simple clinical trials: do they really help?

Authors:  Jonathan J Shuster
Journal:  Stat Med       Date:  2005-08-30       Impact factor: 2.373

3.  Power estimation for rank tests using censored data: conditional and unconditional.

Authors:  A B Cantor
Journal:  Control Clin Trials       Date:  1991-08

4.  How conservative is Fisher's exact test? A quantitative evaluation of the two-sample comparative binomial trial.

Authors:  Gerald G Crans; Jonathan J Shuster
Journal:  Stat Med       Date:  2008-08-15       Impact factor: 2.373

5.  An approximate distribution of estimates of variance components.

Authors:  F E SATTERTHWAITE
Journal:  Biometrics       Date:  1946-12       Impact factor: 2.571

Review 6.  Power and sample size.

Authors:  L Douglas Case; Walter T Ambrosius
Journal:  Methods Mol Biol       Date:  2007

Review 7.  Review of nonparametric methods for the analysis of crossover studies.

Authors:  G Tudor; G G Koch
Journal:  Stat Methods Med Res       Date:  1994-12       Impact factor: 3.021

  7 in total
  8 in total

1.  Data transformation practices in biomedical sciences.

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Journal:  Nat Methods       Date:  2011-02       Impact factor: 28.547

2.  Linear combinations come alive in crossover designs.

Authors:  Jonathan J Shuster
Journal:  Stat Med       Date:  2017-07-06       Impact factor: 2.373

3.  Control in the middle (CIM) for three-period crossover studies.

Authors:  Jonathan Shuster; Stephen D Anton; Douglas Theriaque; Saunjoo Yoon
Journal:  Planta Med       Date:  2011-04-20       Impact factor: 3.352

Review 4.  Design and statistical analysis of oral medicine studies: common pitfalls.

Authors:  L Baccaglini; J J Shuster; J Cheng; D W Theriaque; V J Schoenbach; S L Tomar; C Poole
Journal:  Oral Dis       Date:  2009-10-23       Impact factor: 3.511

5.  To test or not to test: Preliminary assessment of normality when comparing two independent samples.

Authors:  Justine Rochon; Matthias Gondan; Meinhard Kieser
Journal:  BMC Med Res Methodol       Date:  2012-06-19       Impact factor: 4.615

6.  Characteristics, Opportunities, and Challenges of Osteopathy (COCO) in the Perceptions of Osteopaths in Germany, Austria, and Switzerland: Protocol for a Comprehensive Mixed Methods Study.

Authors:  Jan Porthun; Jonas Manschel
Journal:  JMIR Res Protoc       Date:  2019-12-18

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Authors:  Hiroki Watanabe; Aiki Marushima; Hideki Kadone; Yukiyo Shimizu; Shigeki Kubota; Tenyu Hino; Masayuki Sato; Yoshiro Ito; Mikito Hayakawa; Hideo Tsurushima; Kazushi Maruo; Yasushi Hada; Eiichi Ishikawa; Yuji Matsumaru
Journal:  Front Neurosci       Date:  2021-07-02       Impact factor: 4.677

8.  Brain-Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of 1990-1991 Gulf War Veterans in the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study.

Authors:  Lea Steele; Nancy Klimas; Maxine Krengel; Emily Quinn; Rosemary Toomey; Deborah Little; Maria Abreu; Kristina Aenlle; Ronald Killiany; Bang-Bon Koo; Patricia Janulewicz; Timothy Heeren; Allison N Clark; Joy Ajama; Joanna Cirillo; Gerardo Buentello; Vanesa Lerma; Janet K Coller; Kimberly Sullivan
Journal:  Brain Sci       Date:  2021-08-26
  8 in total

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