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Literature DB >> 19270182

Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators.

Shalender Bhasin, Mark A Espeland, William J Evans, Luigi Ferrucci, Linda P Fried, Thomas M Gill, Marco Pahor, Stephanie Studenski, Jack Guralnik, Susan Nayfield, Sergei Romashkin, Robert Perlstein, Laurie Burke, Mary Parks.

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Year: 2009 PMID： 19270182 PMCID： PMC2657175 DOI： 10.1093/gerona/gln042

Source DB: PubMed Journal: J Gerontol A Biol Sci Med Sci ISSN： 1079-5006 Impact factor: 6.053

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31 in total

Review 1. Frailty and hormones.

Authors: John E Morley; Moon Jong Kim; Matthew T Haren
Journal: Rev Endocr Metab Disord Date: 2005-05 Impact factor: 6.514

2. Functional outcomes for clinical trials in frail older persons: time to be moving.

Authors:
Journal: J Gerontol A Biol Sci Med Sci Date: 2008-02 Impact factor: 6.053

3. A prospective study of outcome from protein-energy malnutrition in nursing home residents.

Authors: D R Thomas; R B Verdery; L Gardner; A Kant; J Lindsay
Journal: JPEN J Parenter Enteral Nutr Date: 1991 Jul-Aug Impact factor: 4.016

Review 4. Vitamin D in the aging musculoskeletal system: an authentic strength preserving hormone.

Authors: Manuel Montero-Odasso; Gustavo Duque
Journal: Mol Aspects Med Date: 2005-06

5. Epidemiology of sarcopenia among the elderly in New Mexico.

Authors: R N Baumgartner; K M Koehler; D Gallagher; L Romero; S B Heymsfield; R R Ross; P J Garry; R D Lindeman
Journal: Am J Epidemiol Date: 1998-04-15 Impact factor: 4.897

6. Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density.

Authors: Marianne C Walsh; Gary R Hunter; Margaret Barbara Livingstone
Journal: Osteoporos Int Date: 2005-07-02 Impact factor: 4.507

Review 7. What is sarcopenia?

Authors: W J Evans
Journal: J Gerontol A Biol Sci Med Sci Date: 1995-11 Impact factor: 6.053

8. Sarcopenia is related to physical functioning and leg strength in middle-aged women.

Authors: MaryFran R Sowers; Mary Crutchfield; Kerry Richards; Margaret K Wilkin; Anna Furniss; Mary Jannausch; Daowen Zhang; Melissa Gross
Journal: J Gerontol A Biol Sci Med Sci Date: 2005-04 Impact factor: 6.053

9. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort.

Authors: Anne B Newman; Varant Kupelian; Marjolein Visser; Eleanor M Simonsick; Bret H Goodpaster; Stephen B Kritchevsky; Frances A Tylavsky; Susan M Rubin; Tamara B Harris
Journal: J Gerontol A Biol Sci Med Sci Date: 2006-01 Impact factor: 6.053

10. Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle.

Authors: Shalender Bhasin; Linda Woodhouse; Richard Casaburi; Atam B Singh; Ricky Phong Mac; Martin Lee; Kevin E Yarasheski; Indrani Sinha-Hikim; Connie Dzekov; Jeanne Dzekov; Lynne Magliano; Thomas W Storer
Journal: J Clin Endocrinol Metab Date: 2004-11-23 Impact factor: 5.958

12 in total

Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators.

Review 1. Frailty and hormones.

2. Functional outcomes for clinical trials in frail older persons: time to be moving.

3. A prospective study of outcome from protein-energy malnutrition in nursing home residents.

Review 4. Vitamin D in the aging musculoskeletal system: an authentic strength preserving hormone.

5. Epidemiology of sarcopenia among the elderly in New Mexico.

6. Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density.

Review 7. What is sarcopenia?

8. Sarcopenia is related to physical functioning and leg strength in middle-aged women.

9. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort.

10. Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle.

1. Qualities of fatigue and associated chronic conditions among older adults.

2. Immune aging and challenges for immune protection of the graying population.

3. Novel strategies for improving physical function.

4. Cognitive remediation to enhance mobility in older adults: the CREM study.

5. [Drug therapy in the elderly].

Review 6. Medication use and functional status decline in older adults: a narrative review.

7. The demographic and biomedical case for late-life interventions in aging.

Review 8. Comparative Approaches to Understanding the Relation Between Aging and Physical Function.

9. What are the outcomes of treatment among patients with sarcopenia?

10. Target population for clinical trials.