Literature DB >> 19224209

Incorporation of wavelet-based denoising in iterative deconvolution for partial volume correction in whole-body PET imaging.

N Boussion1, C Cheze Le Rest, M Hatt, D Visvikis.   

Abstract

PURPOSE: Partial volume effects (PVEs) are consequences of the limited resolution of emission tomography. The aim of the present study was to compare two new voxel-wise PVE correction algorithms based on deconvolution and wavelet-based denoising.
MATERIALS AND METHODS: Deconvolution was performed using the Lucy-Richardson and the Van-Cittert algorithms. Both of these methods were tested using simulated and real FDG PET images. Wavelet-based denoising was incorporated into the process in order to eliminate the noise observed in classical deconvolution methods.
RESULTS: Both deconvolution approaches led to significant intensity recovery, but the Van-Cittert algorithm provided images of inferior qualitative appearance. Furthermore, this method added massive levels of noise, even with the associated use of wavelet-denoising. On the other hand, the Lucy-Richardson algorithm combined with the same denoising process gave the best compromise between intensity recovery, noise attenuation and qualitative aspect of the images.
CONCLUSION: The appropriate combination of deconvolution and wavelet-based denoising is an efficient method for reducing PVEs in emission tomography.

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Year:  2009        PMID: 19224209     DOI: 10.1007/s00259-009-1065-5

Source DB:  PubMed          Journal:  Eur J Nucl Med Mol Imaging        ISSN: 1619-7070            Impact factor:   9.236


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