Literature DB >> 19180577

The attitude of women toward current and future possibilities of diagnostic testing in maternal blood using fetal DNA.

Loes Kooij1, Tjeerd Tymstra, Paul van den Berg.   

Abstract

OBJECTIVE: To determine the opinions of women about the new developments in the field of noninvasive prenatal diagnosis (NIPD).
METHOD: Prospective study using questionnaires in two groups of women: women visiting the University Medical Centre Groningen and the Martini Hospital Groningen for the routine fetal anomaly ultrasound scan at 20 weeks' gestation and female medical master students.
RESULTS: Both groups consider NIPD an important asset in the reliable diagnosis of fetal aneuploidy and gender-determined genetic disorders, with the exception of disorders manifesting themselves later in life. There is a negative response as to its application for family balancing. Eighty-two percent of the pregnant women and 79% of the medical students responded positively to the question whether they consider NIPD an important asset in prenatal care. The statement that it is an asset because it enables pregnant women to bear an 'optimal child' is strongly rejected by both groups.
CONCLUSIONS: NIPD paves the way for screening on a large scale. Our survey shows that women feel positive about these new possibilities, but find it hard to fully realize the consequences and new choices they will be confronted with. Copyright (c) 2009 John Wiley & Sons, Ltd.

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Year:  2009        PMID: 19180577     DOI: 10.1002/pd.2205

Source DB:  PubMed          Journal:  Prenat Diagn        ISSN: 0197-3851            Impact factor:   3.050


  15 in total

1.  Non-invasive prenatal testing: ethical issues explored.

Authors:  Antina de Jong; Wybo J Dondorp; Christine E M de Die-Smulders; Suzanne G M Frints; Guido M W R de Wert
Journal:  Eur J Hum Genet       Date:  2009-12-02       Impact factor: 4.246

2.  Demographic and experiential correlates of public attitudes towards cell-free fetal DNA screening.

Authors:  Lauren C Sayres; Megan Allyse; Taylor A Goodspeed; Mildred K Cho
Journal:  J Genet Couns       Date:  2014-04-09       Impact factor: 2.537

3.  Non-invasive prenatal diagnosis for fetal sex determination: benefits and disadvantages from the service users' perspective.

Authors:  Celine Lewis; Melissa Hill; Heather Skirton; Lyn S Chitty
Journal:  Eur J Hum Genet       Date:  2012-03-28       Impact factor: 4.246

4.  Noninvasive prenatal diagnosis: pregnant women's interest and expected uptake.

Authors:  Reana Tischler; Louanne Hudgins; Yair J Blumenfeld; Henry T Greely; Kelly E Ormond
Journal:  Prenat Diagn       Date:  2011-10-26       Impact factor: 3.050

5.  Prenatal testing for Down syndrome: the perspectives of parents of individuals with Down syndrome.

Authors:  Angela Inglis; Catriona Hippman; Jehannine C Austin
Journal:  Am J Med Genet A       Date:  2012-02-21       Impact factor: 2.802

6.  NIPT in a clinical setting: an analysis of uptake in the first months of clinical availability.

Authors:  Joanne B Taylor; Valerie Y Chock; Louanne Hudgins
Journal:  J Genet Couns       Date:  2013-05-31       Impact factor: 2.537

7.  What women want: lead considerations for current and future applications of noninvasive prenatal testing in prenatal care.

Authors:  Ruth M Farrell; Patricia K Agatisa; Benjamin Nutter
Journal:  Birth       Date:  2014-05-14       Impact factor: 3.689

8.  Non-invasive prenatal testing for single gene disorders: exploring the ethics.

Authors:  Zuzana Deans; Melissa Hill; Lyn S Chitty; Celine Lewis
Journal:  Eur J Hum Genet       Date:  2012-11-28       Impact factor: 4.246

9.  Attitudes of pregnant women and male partners towards non-invasive prenatal testing and widening the scope of prenatal screening.

Authors:  Rachèl V van Schendel; Johanna H Kleinveld; Wybo J Dondorp; Eva Pajkrt; Danielle R M Timmermans; Kim C A Holtkamp; Margreet Karsten; Anne L Vlietstra; Augusta M A Lachmeijer; Lidewij Henneman
Journal:  Eur J Hum Genet       Date:  2014-03-19       Impact factor: 4.246

10.  Knowledge, Attitudes, Willingness to Pay, and Patient Preferences About Genetic Testing and Subsequent Risk Management for Cancer Prevention.

Authors:  Fangjian Guo; Jacqueline M Hirth; Erika L Fuchs; Leslie E Cofie; Veronica Brown; Yong-Fang Kuo; Maria E Fernandez; Abbey B Berenson
Journal:  J Cancer Educ       Date:  2022-04       Impact factor: 2.037

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