Pd and CO--ureally got me! The title reaction proceeds efficiently at 18 degrees C under CO (1 atm) with 5 % [Pd(OTs)(2)(MeCN)(2)] as precatalyst. Depending on the solvents used, either anthranilates or cyclic imides can be obtained in high yields (see picture, BQ = benzoquinone, Ts = 4-toluenesulfonyl).
Pd and n class="Chemical">CO--ureally got me! The title reaction proceeds efficiently at 18 degrees C under CO (1 atm) with 5 % [Pd(OTs)(2)(MeCN)(2)] as precatalyst. Depending on the solvents used, either anthranilates or cyclic imides can be obtained in high yields (see picture, BQ = benzoquinone, Ts = 4-toluenesulfonyl).
Authors: Chris E Houlden; Chris D Bailey; J Gair Ford; Michel R Gagné; Guy C Lloyd-Jones; Kevin I Booker-Milburn Journal: J Am Chem Soc Date: 2008-07-10 Impact factor: 15.419
Authors: Marc Hutchby; Chris E Houlden; J Gair Ford; Simon N G Tyler; Michel R Gagné; Guy C Lloyd-Jones; Kevin I Booker-Milburn Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336