Literature DB >> 19132009

Senescence-messaging secretome: SMS-ing cellular stress.

Thomas Kuilman1, Daniel S Peeper.   

Abstract

Oncogene-induced cellular senescence constitutes a strong anti-proliferative response, which can be set in motion following either oncogene activation or loss of tumour suppressor signalling. It serves to limit the expansion of early neoplastic cells and as such is a potent cancer-protective response to oncogenic events. Recently emerging evidence points to a crucial role in oncogene-induced cellular senescence for the 'senescence-messaging secretome' or SMS, setting the stage for cross-talk between senescent cells and their environment. How are such signals integrated into a coordinated response and what are the implications of this unexpected finding?

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Year:  2009        PMID： 19132009     DOI： 10.1038/nrc2560

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  143 in total

1.  LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation.

Authors:  J Herz; D E Clouthier; R E Hammer
Journal:  Cell       Date:  1992-10-30       Impact factor: 41.582

2.  The type V transforming growth factor beta receptor is the putative insulin-like growth factor-binding protein 3 receptor.

Authors:  S M Leal; Q Liu; S S Huang; J S Huang
Journal:  J Biol Chem       Date:  1997-08-15       Impact factor: 5.157

3.  Genes for insulin-like growth factors I and II are expressed in senescent rat tissues.

Authors:  G H Park; D E Buetow
Journal:  Gerontology       Date:  1991       Impact factor: 5.140

4.  A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation.

Authors:  Masashi Narita; Masako Narita; Valery Krizhanovsky; Sabrina Nuñez; Agustin Chicas; Stephen A Hearn; Michael P Myers; Scott W Lowe
Journal:  Cell       Date:  2006-08-11       Impact factor: 41.582

5.  Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation.

Authors:  A Damalas; S Kahan; M Shtutman; A Ben-Ze'ev; M Oren
Journal:  EMBO J       Date:  2001-09-03       Impact factor: 11.598

6.  Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3'-kinase/Akt signaling pathway.

Authors:  M V Chakravarthy; T W Abraha; R J Schwartz; M L Fiorotto; F W Booth
Journal:  J Biol Chem       Date:  2000-11-17       Impact factor: 5.157

7.  Aberrant promoter methylation of insulin-like growth factor binding protein-3 gene in human cancers.

Authors:  Kunitoshi Tomii; Kazunori Tsukuda; Shinichi Toyooka; Hideaki Dote; Tadashi Hanafusa; Hiroaki Asano; Minoru Naitou; Hiroyoshi Doihara; Takumi Kisimoto; Hideki Katayama; Harvery I Pass; Hiroshi Date; Nobuyoshi Shimizu
Journal:  Int J Cancer       Date:  2007-02-01       Impact factor: 7.396

8.  Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

Authors:  K Orth; E L Madison; M J Gething; J F Sambrook; J Herz
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

9.  Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma.

Authors:  A B Glick; M M Lee; N Darwiche; A B Kulkarni; S Karlsson; S H Yuspa
Journal:  Genes Dev       Date:  1994-10-15       Impact factor: 11.361

10.  Insulin-like growth factor binding protein-5 (IGFBP-5) suppresses the tumourigenesis of head and neck squamous cell carcinoma.

Authors:  P-S Hung; S-Y Kao; Y-H Shih; S-H Chiou; C-J Liu; K-W Chang; S-C Lin
Journal:  J Pathol       Date:  2008-02       Impact factor: 7.996
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  363 in total

1.  Chronic sleep fragmentation induces endothelial dysfunction and structural vascular changes in mice.

Authors:  Alba Carreras; Shelley X Zhang; Eduard Peris; Zhuanhong Qiao; Alex Gileles-Hillel; Richard C Li; Yang Wang; David Gozal
Journal:  Sleep       Date:  2014-11-01       Impact factor: 5.849

2.  Spatial coupling of mTOR and autophagy augments secretory phenotypes.

Authors:  Masako Narita; Andrew R J Young; Satoko Arakawa; Shamith A Samarajiwa; Takayuki Nakashima; Sei Yoshida; Sungki Hong; Lorraine S Berry; Stefanie Reichelt; Manuela Ferreira; Simon Tavaré; Ken Inoki; Shigeomi Shimizu; Masashi Narita
Journal:  Science       Date:  2011-04-21       Impact factor: 47.728

3.  Cancer: final act of senescence.

Authors:  Manuel Serrano
Journal:  Nature       Date:  2011-11-23       Impact factor: 49.962

4.  Ageing: Old cells under attack.

Authors:  Daniel S Peeper
Journal:  Nature       Date:  2011-11-09       Impact factor: 49.962

5.  Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia.

Authors:  Mitsuro Kanda; Hanno Matthaei; Jian Wu; Seung-Mo Hong; Jun Yu; Michael Borges; Ralph H Hruban; Anirban Maitra; Kenneth Kinzler; Bert Vogelstein; Michael Goggins
Journal:  Gastroenterology       Date:  2012-01-05       Impact factor: 22.682

6.  Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.

Authors:  Celia Quijano; Liu Cao; Maria M Fergusson; Hector Romero; Jie Liu; Sarah Gutkind; Ilsa I Rovira; Robert P Mohney; Edward D Karoly; Toren Finkel
Journal:  Cell Cycle       Date:  2012-04-01       Impact factor: 4.534

Review 7.  Inflammatory networks during cellular senescence: causes and consequences.

Authors:  Adam Freund; Arturo V Orjalo; Pierre-Yves Desprez; Judith Campisi
Journal:  Trends Mol Med       Date:  2010-05-03       Impact factor: 11.951

Review 8.  The essence of senescence.

Authors:  Thomas Kuilman; Chrysiis Michaloglou; Wolter J Mooi; Daniel S Peeper
Journal:  Genes Dev       Date:  2010-11-15       Impact factor: 11.361

Review 9.  Senescent cells: an emerging target for diseases of ageing.

Authors:  Bennett G Childs; Martina Gluscevic; Darren J Baker; Remi-Martin Laberge; Dan Marquess; Jamie Dananberg; Jan M van Deursen
Journal:  Nat Rev Drug Discov       Date:  2017-07-21       Impact factor: 84.694

10.  PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.

Authors:  Mesut Eren; Amanda E Boe; Sheila B Murphy; Aaron T Place; Varun Nagpal; Luisa Morales-Nebreda; Daniela Urich; Susan E Quaggin; G R Scott Budinger; Gökhan M Mutlu; Toshio Miyata; Douglas E Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-28       Impact factor: 11.205
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