Literature DB >> 19129834

Organic chemistry: Molecular diversity by design.

Stuart L Schreiber.   

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Year:  2009        PMID： 19129834     DOI： 10.1038/457153a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  9 in total

1.  Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

Authors:  Finny G Kuruvilla; Alykhan F Shamji; Scott M Sternson; Paul J Hergenrother; Stuart L Schreiber
Journal:  Nature       Date:  2002-04-11       Impact factor: 49.962

Review 2.  Drugs for bad bugs: confronting the challenges of antibacterial discovery.

Authors:  David J Payne; Michael N Gwynn; David J Holmes; David L Pompliano
Journal:  Nat Rev Drug Discov       Date:  2006-12-08       Impact factor: 84.694

3.  Anti-MRSA agent discovery using diversity-oriented synthesis.

Authors:  Gemma L Thomas; Richard J Spandl; Freija G Glansdorp; Martin Welch; Andreas Bender; Joshua Cockfield; Jodi A Lindsay; Clare Bryant; Derek F J Brown; Olivier Loiseleur; Hélène Rudyk; Mark Ladlow; David R Spring
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.

Authors:  Pui Yee Ng; Yuchen Tang; Wendy M Knosp; H Scott Stadler; Jared T Shaw
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

5.  The principles of conformational analysis.

Authors:  D H Barton
Journal:  Science       Date:  1970-08-07       Impact factor: 47.728

6.  Natural product synthesis and vitamin B12.

Authors:  A Eschenmoser; C E Wintner
Journal:  Science       Date:  1977-06-24       Impact factor: 47.728

7.  Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.

Authors:  Angela N Koehler; Alykhan F Shamji; Stuart L Schreiber
Journal:  J Am Chem Soc       Date:  2003-07-16       Impact factor: 15.419

Review 8.  Towards the optimal screening collection: a synthesis strategy.

Authors:  Thomas E Nielsen; Stuart L Schreiber
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

9.  Synthesis of natural-product-like molecules with over eighty distinct scaffolds.

Authors:  Daniel Morton; Stuart Leach; Christopher Cordier; Stuart Warriner; Adam Nelson
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336
  9 in total
  61 in total

1.  Medicinal chemistry for 2020.

Authors:  Seetharama D Satyanarayanajois; Ronald A Hill
Journal:  Future Med Chem       Date:  2011-10       Impact factor: 3.808

2.  Catalytic diastereoselective petasis reactions.

Authors:  Giovanni Muncipinto; Philip N Moquist; Stuart L Schreiber; Scott E Schaus
Journal:  Angew Chem Int Ed Engl       Date:  2011-07-12       Impact factor: 15.336

Review 3.  Chemical probes and drug leads from advances in synthetic planning and methodology.

Authors:  Christopher J Gerry; Stuart L Schreiber
Journal:  Nat Rev Drug Discov       Date:  2018-04-13       Impact factor: 84.694

4.  Drug discovery: A question of library design.

Authors:  Philip J Hajduk; Warren R J D Galloway; David R Spring
Journal:  Nature       Date:  2011-02-03       Impact factor: 49.962

5.  Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles.

Authors:  Eamon Comer; Haibo Liu; Adrien Joliton; Alexandre Clabaut; Christopher Johnson; Lakshmi B Akella; Lisa A Marcaurelle
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-07       Impact factor: 11.205

6.  Diversity-oriented synthesis of macrocyclic peptidomimetics.

Authors:  Albert Isidro-Llobet; Tiffanie Murillo; Paula Bello; Agostino Cilibrizzi; James T Hodgkinson; Warren R J D Galloway; Andreas Bender; Martin Welch; David R Spring
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-07       Impact factor: 11.205

7.  Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions.

Authors:  Bhaumik A Pandya; Sivaraman Dandapani; Jeremy R Duvall; Ann Rowley; Carol A Mulrooney; Troy Ryba; Michael Dombrowski; Marie Harton; Damian W Young; Lisa A Marcaurelle
Journal:  Tetrahedron       Date:  2011-08-26       Impact factor: 2.457

8.  Do We Build Similar Molecules for Comorbid Diseases? Tevarud in Drug Design, an Analysis for Depression and Inflammation.

Authors:  F Esra Önen Bayram; Sarah A A Alradhwani; Gulcin Tugcu; Hande Sipahi
Journal:  ACS Med Chem Lett       Date:  2020-01-16       Impact factor: 4.345

Review 9.  Expanding the number of 'druggable' targets: non-enzymes and protein-protein interactions.

Authors:  Leah N Makley; Jason E Gestwicki
Journal:  Chem Biol Drug Des       Date:  2013-01       Impact factor: 2.817

10.  Stereochemical and skeletal diversity arising from amino propargylic alcohols.

Authors:  Daniela Pizzirani; Taner Kaya; Paul A Clemons; Stuart L Schreiber
Journal:  Org Lett       Date:  2010-06-18       Impact factor: 6.005
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