Literature DB >> 17568465

Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.

Pui Yee Ng1, Yuchen Tang, Wendy M Knosp, H Scott Stadler, Jared T Shaw.   

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Year:  2007        PMID： 17568465     DOI： 10.1002/anie.200700762

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  24 in total

1.  Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules.

Authors:  Warren R J D Galloway; Albert Isidro-Llobet; David R Spring
Journal:  Nat Commun       Date:  2010-09-21       Impact factor: 14.919

2.  Organic chemistry: Molecular diversity by design.

Authors:  Stuart L Schreiber
Journal:  Nature       Date:  2009-01-08       Impact factor: 49.962

Review 3.  Chemical probes and drug leads from advances in synthetic planning and methodology.

Authors:  Christopher J Gerry; Stuart L Schreiber
Journal:  Nat Rev Drug Discov       Date:  2018-04-13       Impact factor: 84.694

4.  A general method for discovering inhibitors of protein-DNA interactions using photonic crystal biosensors.

Authors:  Leo L Chan; Maria Pineda; James T Heeres; Paul J Hergenrother; Brian T Cunningham
Journal:  ACS Chem Biol       Date:  2008-07-18       Impact factor: 5.100

5.  Diversity-oriented synthesis of macrocyclic peptidomimetics.

Authors:  Albert Isidro-Llobet; Tiffanie Murillo; Paula Bello; Agostino Cilibrizzi; James T Hodgkinson; Warren R J D Galloway; Andreas Bender; Martin Welch; David R Spring
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-07       Impact factor: 11.205

6.  The transcription factor FOXM1 is a cellular target of the natural product thiostrepton.

Authors:  Nagaratna S Hegde; Deborah A Sanders; Raphaël Rodriguez; Shankar Balasubramanian
Journal:  Nat Chem       Date:  2011-08-21       Impact factor: 24.427

7.  Stereochemistry and Reactivity of the HPA-Imine Mannich Intermediate.

Authors:  Daniel Polyak; Ngan Phung; Jian Liu; Robert Barrows; Thomas J Emge; Spencer Knapp
Journal:  Tetrahedron Lett       Date:  2017-08-31       Impact factor: 2.415

8.  The p53-MDM2/MDMX axis - A chemotype perspective.

Authors:  Kareem Khoury; Grzegorz M Popowicz; Tad A Holak; Alexander Dömling
Journal:  Medchemcomm       Date:  2011       Impact factor: 3.597

9.  Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.

Authors:  Nobutaka Kato; Eamon Comer; Tomoyo Sakata-Kato; Arvind Sharma; Manmohan Sharma; Micah Maetani; Jessica Bastien; Nicolas M Brancucci; Joshua A Bittker; Victoria Corey; David Clarke; Emily R Derbyshire; Gillian L Dornan; Sandra Duffy; Sean Eckley; Maurice A Itoe; Karin M J Koolen; Timothy A Lewis; Ping S Lui; Amanda K Lukens; Emily Lund; Sandra March; Elamaran Meibalan; Bennett C Meier; Jacob A McPhail; Branko Mitasev; Eli L Moss; Morgane Sayes; Yvonne Van Gessel; Mathias J Wawer; Takashi Yoshinaga; Anne-Marie Zeeman; Vicky M Avery; Sangeeta N Bhatia; John E Burke; Flaminia Catteruccia; Jon C Clardy; Paul A Clemons; Koen J Dechering; Jeremy R Duvall; Michael A Foley; Fabian Gusovsky; Clemens H M Kocken; Matthias Marti; Marshall L Morningstar; Benito Munoz; Daniel E Neafsey; Amit Sharma; Elizabeth A Winzeler; Dyann F Wirth; Christina A Scherer; Stuart L Schreiber
Journal:  Nature       Date:  2016-09-07       Impact factor: 49.962

10.  N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli.

Authors:  Shubhasish Mukherjee; Carolyn A Robinson; Andrew G Howe; Tali Mazor; Peter A Wood; Sameer Urgaonkar; Alan M Hebert; Debabrata Raychaudhuri; Jared T Shaw
Journal:  Bioorg Med Chem Lett       Date:  2007-09-07       Impact factor: 2.823
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