Literature DB >> 18307176

Anti-MRSA agent discovery using diversity-oriented synthesis.

Gemma L Thomas1, Richard J Spandl, Freija G Glansdorp, Martin Welch, Andreas Bender, Joshua Cockfield, Jodi A Lindsay, Clare Bryant, Derek F J Brown, Olivier Loiseleur, Hélène Rudyk, Mark Ladlow, David R Spring.   

Abstract

Mesh：

Substances：

Year:  2008        PMID： 18307176     DOI： 10.1002/anie.200705415

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  27 in total

1.  Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules.

Authors:  Warren R J D Galloway; Albert Isidro-Llobet; David R Spring
Journal:  Nat Commun       Date:  2010-09-21       Impact factor: 14.919

2.  Organic chemistry: Molecular diversity by design.

Authors:  Stuart L Schreiber
Journal:  Nature       Date:  2009-01-08       Impact factor: 49.962

3.  A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.

Authors:  Henning S G Beckmann; Feilin Nie; Caroline E Hagerman; Henrik Johansson; Yaw Sing Tan; David Wilcke; David R Spring
Journal:  Nat Chem       Date:  2013-08-25       Impact factor: 24.427

Review 4.  Chemical probes and drug leads from advances in synthetic planning and methodology.

Authors:  Christopher J Gerry; Stuart L Schreiber
Journal:  Nat Rev Drug Discov       Date:  2018-04-13       Impact factor: 84.694

5.  Diversity-oriented synthesis of macrocyclic peptidomimetics.

Authors:  Albert Isidro-Llobet; Tiffanie Murillo; Paula Bello; Agostino Cilibrizzi; James T Hodgkinson; Warren R J D Galloway; Andreas Bender; Martin Welch; David R Spring
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-07       Impact factor: 11.205

6.  Synthesis of Diverse Heterocyclic Scaffolds via Tandem Additions to Imine Derivatives and Ring-Forming Reactions.

Authors:  James D Sunderhaus; Chris Dockendorff; Stephen F Martin
Journal:  Tetrahedron       Date:  2009-09-15       Impact factor: 2.457

7.  Diversity through a branched reaction pathway: generation of multicyclic scaffolds and identification of antimigratory agents.

Authors:  Zhiming Wang; Sabrina Castellano; Sape S Kinderman; Christian E Argueta; Anwar B Beshir; Gabriel Fenteany; Ohyun Kwon
Journal:  Chemistry       Date:  2010-11-09       Impact factor: 5.236

Review 8.  Natural Products as Platforms To Overcome Antibiotic Resistance.

Authors:  Sean E Rossiter; Madison H Fletcher; William M Wuest
Journal:  Chem Rev       Date:  2017-09-27       Impact factor: 60.622

Review 9.  Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective.

Authors:  Renato A Bauer; Jacqueline M Wurst; Derek S Tan
Journal:  Curr Opin Chem Biol       Date:  2010-03-02       Impact factor: 8.822

10.  Identification of a broad-spectrum inhibitor of viral RNA synthesis: validation of a prototype virus-based approach.

Authors:  Claire Marie Filone; Erin N Hodges; Brian Honeyman; G Guy Bushkin; Karla Boyd; Andrew Platt; Feng Ni; Kyle Strom; Lisa Hensley; John K Snyder; John H Connor
Journal:  Chem Biol       Date:  2013-03-21
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.