Literature DB >> 19126455

A legged anchoring mechanism for capsule endoscopes using micropatterned adhesives.

Paul Glass1, Eugene Cheung, Metin Sitti.   

Abstract

This paper presents a new concept for an anchoring mechanism to enhance existing capsule endoscopes. The mechanism consists of three actuated legs with compliant feet lined with micropillar adhesives to be pressed into the intestine wall to anchor the device at a fixed location. These adhesive systems are inspired by gecko and beetle foot hairs. Single-leg and full capsule mathematical models of the forces generated by the legs are analyzed to understand capsule performance. Empirical friction models for the interaction of the adhesives with an intestinal substrate were experimentally determined in vitro using dry and oil-coated elastomer micropillar arrays with 140 microm pillar diameter, 105 microm spacing between pillars, and an aspect ratio of 1:1 on fresh porcine small intestine specimens. Capsule prototypes were also tested in a simulated intestine environment and compared with predicted peristaltic loads to assess the viability of the proposed design. The experimental results showed that a deployed 10 gr capsule robot can withstand axial peristaltic loads and anchor reliably when actuation forces are greater than 0.27 N using dry micropillars. Required actuation forces may be reduced significantly by using micropillars coated with a thin silicone oil layer.

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Year:  2008        PMID: 19126455     DOI: 10.1109/TBME.2008.2002111

Source DB:  PubMed          Journal:  IEEE Trans Biomed Eng        ISSN: 0018-9294            Impact factor:   4.538


  20 in total

1.  Preliminary mechanical characterization of the small bowel for in vivo robotic mobility.

Authors:  Benjamin S Terry; Allison B Lyle; Jonathan A Schoen; Mark E Rentschler
Journal:  J Biomech Eng       Date:  2011-09       Impact factor: 2.097

Review 2.  Capsule endoscopy of the future: What's on the horizon?

Authors:  Piotr R Slawinski; Keith L Obstein; Pietro Valdastri
Journal:  World J Gastroenterol       Date:  2015-10-07       Impact factor: 5.742

Review 3.  Wireless endoscopy in 2020: Will it still be a capsule?

Authors:  Anastasios Koulaouzidis; Dimitris K Iakovidis; Alexandros Karargyris; Emanuele Rondonotti
Journal:  World J Gastroenterol       Date:  2015-05-07       Impact factor: 5.742

4.  Surgical evaluation of a novel tethered robotic capsule endoscope using micro-patterned treads.

Authors:  Levin J Sliker; Madalyn D Kern; Jonathan A Schoen; Mark E Rentschler
Journal:  Surg Endosc       Date:  2012-04-27       Impact factor: 4.584

Review 5.  Small-bowel capsule endoscopy: a ten-point contemporary review.

Authors:  Anastasios Koulaouzidis; Emanuele Rondonotti; Alexandros Karargyris
Journal:  World J Gastroenterol       Date:  2013-06-28       Impact factor: 5.742

6.  Capsule-odometer: a concept to improve accurate lesion localisation.

Authors:  Alexandros Karargyris; Anastasios Koulaouzidis
Journal:  World J Gastroenterol       Date:  2013-09-21       Impact factor: 5.742

7.  Telemetry system for slow wave measurement from the small bowel.

Authors:  S H Woo; J H Cho
Journal:  Med Biol Eng Comput       Date:  2009-12-29       Impact factor: 2.602

8.  Stopping mechanism for capsule endoscope using electrical stimulus.

Authors:  Sang Hyo Woo; Tae Wan Kim; Jin Ho Cho
Journal:  Med Biol Eng Comput       Date:  2009-11-13       Impact factor: 2.602

9.  Measurements of the contact force from myenteric contractions on a solid bolus.

Authors:  Benjamin S Terry; Jonathan A Schoen; Mark E Rentschler
Journal:  J Robot Surg       Date:  2012-03-14

10.  Biopsy with thermally-responsive untethered microtools.

Authors:  Evin Gultepe; Jatinder S Randhawa; Sachin Kadam; Sumitaka Yamanaka; Florin M Selaru; Eun J Shin; Anthony N Kalloo; David H Gracias
Journal:  Adv Mater       Date:  2012-10-09       Impact factor: 30.849

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