Literature DB >> 19061361

Near-infrared fluorescent pH-sensitive probes via unexpected barbituric acid mediated synthesis.

Hyeran Lee1, Mikhail Y Berezin, Kevin Guo, Jeff Kao, Samuel Achilefu.   

Abstract

Novel near-infrared pyrimidine-fused pH fluorescent probes were prepared by an unusual barbiturate-mediated debenzoindolation and subsequent heteroannulation. A plausible mechanistic pathway is proposed, and the final structures were further elucidated by 2D-NMR. All new compounds are highly fluorescent in the near-infrared region and possess excellent spectral sensitivities to environmental pH changes.

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Year:  2009        PMID： 19061361      PMCID： PMC2725187          DOI： 10.1021/ol802363x

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  9 in total

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Journal:  J Org Chem       Date:  2006-09-29       Impact factor: 4.354

6.  Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: a paradigm for excited-state intramolecular charge transfer.

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9.  Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes.

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  9 in total
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Authors:  Jorge O Escobedo; Oleksandr Rusin; Soojin Lim; Robert M Strongin
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4.  Pyrazole-substituted near-infrared cyanine dyes exhibit pH-dependent fluorescence lifetime properties.

Authors:  Hyeran Lee; Mikhail Y Berezin; Rui Tang; Natalia Zhegalova; Samuel Achilefu
Journal:  Photochem Photobiol       Date:  2012-12-10       Impact factor: 3.421

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7.  Synthesis of a New Amino-Furopyridine-Based Compound as a Novel Fluorescent pH Sensor in Aqueous Solution.

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Journal:  ACS Omega       Date:  2021-02-05
  7 in total

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