| Literature DB >> 16704241 |
Kazuki Kiyose1, Hirotatsu Kojima, Yasuteru Urano, Tetsuo Nagano.
Abstract
Novel ratiometric fluorescent probes for Zn2+ in the near-infrared region, based on a tricarbocyanine chromophore, have been designed, synthesized, and evaluated. Upon addition of Zn2+, a 44 nm red shift of the absorption maximum was observed, which indicates that this probe could work as a ratiometric probe for Zn2+. This change is due to the difference in the electron-donating ability of the amine substituent before and after reaction with Zn2+. This fluorescence modulation of amine-substituted tricarbocyanines should be applicable to dual-wavelength measurement of various biomolecules or enzyme activities.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16704241 DOI： 10.1021/ja060399c
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419