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Literature DB >> 15176820

Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes.

Abstract

[reaction: see text] A new near-infrared (NIR) fluorescent molecular probe derived from indocarbocyanine dye and galactose was prepared, and the procedure was optimized. The presence of a nonionic polyhydroxyl moiety between hydrophobic groups enhances solubility and possibly minimizes aggregation in aqueous solutions. The structural framework of this molecule provides multivalent sites for labeling diverse molecules.

Entities: Chemical

Mesh：

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Year: 2004 PMID： 15176820 DOI： 10.1021/ol049258a

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

14 in total

1. Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry.

Authors: Kristin A Fletcher; Sayo O Fakayode; Mark Lowry; Sheryl A Tucker; Sharon L Neal; Irene W Kimaru; Matthew E McCarroll; Gabor Patonay; Philip B Oldham; Oleksandr Rusin; Robert M Strongin; Isiah M Warner
Journal: Anal Chem Date: 2006-06-15 Impact factor: 6.986

2. Optical imaging of bacterial infection in living mice using a fluorescent near-infrared molecular probe.

Authors: W Matthew Leevy; Seth T Gammon; Hua Jiang; James R Johnson; Dustin J Maxwell; Erin N Jackson; Manuel Marquez; David Piwnica-Worms; Bradley D Smith
Journal: J Am Chem Soc Date: 2006-12-27 Impact factor: 15.419

3. Discovery and early development of squaraine rotaxanes.

Authors: Jeremiah J Gassensmith; Jeffrey M Baumes; Bradley D Smith
Journal: Chem Commun (Camb) Date: 2009-08-24 Impact factor: 6.222

4. Impact of Substituents in Tumor Uptake and Fluorescence Imaging Ability of Near-Infrared Cyanine-like Dyes.

Authors: Nayan J Patel; Ethirajan Manivannan; Penny Joshi; Tymish J Ohulchanskyy; Roger R Nani; Martin J Schnermann; Ravindra K Pandey
Journal: Photochem Photobiol Date: 2015-07-30 Impact factor: 3.421

5. A Benzothiazole-Based Sensor for Pyrophosphate (PPi) and ATP: Mechanistic Insight for Anion-Induced ESIPT Turn-On.

Authors: Junfeng Wang; Xiumin Liu; Yi Pang
Journal: J Mater Chem B Date: 2014-10-14 Impact factor: 6.331

6. Near IR heptamethine cyanine dye-mediated cancer imaging.

Authors: Xiaojian Yang; Chunmeng Shi; Rong Tong; Weiping Qian; Haiyen E Zhau; Ruoxiang Wang; Guodong Zhu; Jianjun Cheng; Vincent W Yang; Tianmin Cheng; Maged Henary; Lucjan Strekowski; Leland W K Chung
Journal: Clin Cancer Res Date: 2010-04-21 Impact factor: 12.531

Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes.

1. Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry.

2. Optical imaging of bacterial infection in living mice using a fluorescent near-infrared molecular probe.

3. Discovery and early development of squaraine rotaxanes.

4. Impact of Substituents in Tumor Uptake and Fluorescence Imaging Ability of Near-Infrared Cyanine-like Dyes.

5. A Benzothiazole-Based Sensor for Pyrophosphate (PPi) and ATP: Mechanistic Insight for Anion-Induced ESIPT Turn-On.

6. Near IR heptamethine cyanine dye-mediated cancer imaging.

7. Alzheimer's disease imaging with a novel Tau targeted near infrared ratiometric probe.

8. Near-infrared fluorescent pH-sensitive probes via unexpected barbituric acid mediated synthesis.

9. Irradiation induced fluorescence enhancement in PEGylated cyanine-based NIR nano- and mesoscale GUMBOS.

10. Evaluation of polymethine dyes as potential probes for near infrared fluorescence imaging of tumors: part - 1.