Literature DB >> 19009325

Case report: reconstruction of a 16-cm diaphyseal defect after Ewing's resection in a child.

David Jean Biau1, Stéphanie Pannier, Alain Charles Masquelet, Christophe Glorion.   

Abstract

Numerous options exist for intercalary segmental reconstruction after bone tumor resection. We present the extension of a recently developed surgical two-stage technique that involves insertion of a cement spacer, induction of a membrane, and reconstruction of the defect with cancellous and cortical bone autograft in a 12-year-old child. The boy was referred to our center for treatment of a right femoral diaphyseal Ewing's sarcoma. The first stage involved resection of the tumor and reconstruction with a locked intramedullary nail and a polymethylmethacrylate cement spacer. Seven months after the initial procedure during which adjuvant chemotherapy was given, the second-stage procedure was performed. The cement was removed and cancellous and cortical bone autograft was grafted in the membrane created around the cement spacer. Touchdown weightbearing was allowed immediately, partial weightbearing was resumed 6 weeks after the operation, and full weightbearing was allowed 4 months later. Successive plain radiographs showed rapid integration of the autograft to the host bone with bone union and cortical reconstitution. The principle of the induced membrane reconstruction seems applicable to intercalary segmental reconstruction after bone tumor resection in children.

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Year:  2008        PMID: 19009325      PMCID: PMC2628508          DOI: 10.1007/s11999-008-0605-9

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  17 in total

1.  Factors affecting nonunion of the allograft-host junction.

Authors:  F J Hornicek; M C Gebhardt; W W Tomford; J I Sorger; M Zavatta; J P Menzner; H J Mankin
Journal:  Clin Orthop Relat Res       Date:  2001-01       Impact factor: 4.176

2.  [Reconstruction of the long bones by the induced membrane and spongy autograft].

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Journal:  Ann Chir Plast Esthet       Date:  2000-06       Impact factor: 0.660

3.  Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes.

Authors:  Elke Ahlmann; Michael Patzakis; Nikolaos Roidis; Lane Shepherd; Paul Holtom
Journal:  J Bone Joint Surg Am       Date:  2002-05       Impact factor: 5.284

4.  Free vascularised fibular grafting for reconstruction after tumour resection.

Authors:  R W Hsu; M B Wood; F H Sim; E Y Chao
Journal:  J Bone Joint Surg Br       Date:  1997-01

5.  Induced membranes secrete growth factors including vascular and osteoinductive factors and could stimulate bone regeneration.

Authors:  Ph Pelissier; A C Masquelet; R Bareille; S Mathoulin Pelissier; J Amedee
Journal:  J Orthop Res       Date:  2004-01       Impact factor: 3.494

6.  A system for the surgical staging of musculoskeletal sarcoma.

Authors:  W F Enneking; S S Spanier; M A Goodman
Journal:  Clin Orthop Relat Res       Date:  1980 Nov-Dec       Impact factor: 4.176

7.  The outcome and functional results of diaphyseal endoprostheses after tumour excision.

Authors:  A Abudu; S R Carter; R J Grimer
Journal:  J Bone Joint Surg Br       Date:  1996-07

8.  Massive allografts in the treatment of osteosarcoma and Ewing sarcoma in children and adolescents.

Authors:  B A Alman; A De Bari; J I Krajbich
Journal:  J Bone Joint Surg Am       Date:  1995-01       Impact factor: 5.284

Review 9.  Intercalary segmental reconstruction after bone tumor resection.

Authors:  B Fuchs; C Ossendorf; T Leerapun; F H Sim
Journal:  Eur J Surg Oncol       Date:  2008-01-11       Impact factor: 4.424

10.  Reconstruction of lower limb bone defects after sarcoma resection in children and adolescents using free vascularized fibular transfer.

Authors:  Tarek Abdalla El-Gammal; Amr El-Sayed; Mohammed M Kotb
Journal:  J Pediatr Orthop B       Date:  2003-07       Impact factor: 1.041

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  16 in total

Review 1.  [Reconstruction of osseous defects using the Masquelet technique].

Authors:  F Saxer; H Eckardt
Journal:  Orthopade       Date:  2017-08       Impact factor: 1.087

2.  Is the Induced-membrane Technique Successful for Limb Reconstruction After Resecting Large Bone Tumors in Children?

Authors:  Frank Fitoussi; Brice Ilharreborde
Journal:  Clin Orthop Relat Res       Date:  2015-01-30       Impact factor: 4.176

Review 3.  Induced membrane for treatment of critical sized bone defect: a review of experimental and clinical experiences.

Authors:  Jean-Charles Aurégan; Thierry Bégué
Journal:  Int Orthop       Date:  2014-07-02       Impact factor: 3.075

4.  Masquelet technique: The effect of altering implant material and topography on membrane matrix composition, mechanical and barrier properties in a rat defect model.

Authors:  Natalie Gaio; Alice Martino; Zacharie Toth; J Tracy Watson; Daemeon Nicolaou; Sarah McBride-Gagyi
Journal:  J Biomech       Date:  2018-02-27       Impact factor: 2.712

5.  Reconstruction of traumatic bone loss using the induced membrane technique: preliminary results about 11 cases.

Authors:  Noufanangue Kanfitine Kombate; Atchi Walla; Gamal Ayouba; B Moïse Bakriga; Yaovi Yannick Dellanh; Anani Grégoire Abalo; Assang Michel Dossim
Journal:  J Orthop       Date:  2017-07-13

6.  Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects.

Authors:  Yash M Kolambkar; Joel D Boerckel; Kenneth M Dupont; Mehmet Bajin; Nathaniel Huebsch; David J Mooney; Dietmar W Hutmacher; Robert E Guldberg
Journal:  Bone       Date:  2011-05-18       Impact factor: 4.398

7.  [Masquelet technique for the treatment of large dia- and metaphyseal bone defects].

Authors:  D Krappinger; R A Lindtner; M Zegg; A Dal Pont; B Huber
Journal:  Oper Orthop Traumatol       Date:  2015-05-29       Impact factor: 1.154

8.  Induced membrane technique for the treatment of congenital pseudarthrosis of the tibia: preliminary results of five cases.

Authors:  Stéphanie Pannier; Zagorka Pejin; Caroline Dana; Alain Charles Masquelet; Christophe Glorion
Journal:  J Child Orthop       Date:  2013-10-08       Impact factor: 1.548

9.  Management of traumatic tibial diaphyseal bone defect by "induced-membrane technique".

Authors:  Gaurav Gupta; Sohail Ahmad; A H Khan; M K A Sherwani; Abdul Qayyum Khan
Journal:  Indian J Orthop       Date:  2016 May-Jun       Impact factor: 1.251

10.  Salvage Reconstruction With the Masquelet Technique Following Wide Resection for Chondrosarcoma of the Proximal Femoral Metaphysis: A Case Report.

Authors:  Michiyuki Hakozaki; Ryoichi Kawakami; Nobuyuki Sasaki; Narihiro Toshiki; Yoichi Kaneuchi; Hitoshi Yamada; Shinichi Konno
Journal:  In Vivo       Date:  2020 Nov-Dec       Impact factor: 2.155

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