Literature DB >> 27293290

Management of traumatic tibial diaphyseal bone defect by "induced-membrane technique".

Gaurav Gupta1, Sohail Ahmad1, A H Khan2, M K A Sherwani1, Abdul Qayyum Khan1.   

Abstract

BACKGROUND: Gap nonunion of long bones is a challenging problem, due to the limitation of conventional reconstructive techniques more so if associated with infection and soft tissue defect. Treatment options such as autograft with non-vascularized fibula and cancellous bone graft, vascularized bone graft, and bone transportation are highly demanding on the part of surgeons and hospital setups and have many drawbacks. This study aims to analyze the outcome of patients with wide diaphyseal bone gap treated with induced-membrane technique (Masquelet technique).
MATERIALS AND METHODS: This study included 9 patients (7 males and 2 females), all with tibial bone-gap. Eight of the 9 patients were infected and in 3 patients there was associated large soft tissue defect requiring flap cover. This technique is two-stage procedure. Stage I surgery included debridement, fracture stabilization, application of spacer between bone ends, and soft tissue reconstruction. Stage II surgery included removal of spacer with preservation of induced membrane formed at spacer surface and filling the bone-gap with morselized iliac crest bone-graft within the membrane sleeve. Average bone-gap of 5.2 cm was treated. The spacer was always found to be encapsulated by a thick glistening membrane which did not collapse after its removal. All patients were followed up for an average period of 21.5 months.
RESULTS: Serial Radiographs showed regular uptake of autograft and thus consolidation within themselves in the region of bone gap and also with host bone. Bone-union was documented in all patients and all patients are walking full weight-bearing without support.
CONCLUSIONS: The study highlights that the technique provide effective and practical management for difficult gap nonunion. It does not require specialized equipment, investigations, and surgery. Thus, it provides a reasonable alternative to the developing infrastructures and is a reliable and reproducible technique.

Entities:  

Keywords:  Bone-cement spacer; Tibia; bone cements; gap nonunion; induced-membrane technique; posttraumatic

Year:  2016        PMID: 27293290      PMCID: PMC4885298          DOI: 10.4103/0019-5413.181780

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.251


  15 in total

1.  [Reconstruction of the long bones by the induced membrane and spongy autograft].

Authors:  A C Masquelet; F Fitoussi; T Begue; G P Muller
Journal:  Ann Chir Plast Esthet       Date:  2000-06       Impact factor: 0.660

Review 2.  Vascularized autografts for reconstruction of skeletal defects following lower extremity trauma. A review.

Authors:  F R Nusbickel; P C Dell; M P McAndrew; M M Moore
Journal:  Clin Orthop Relat Res       Date:  1989-06       Impact factor: 4.176

3.  Functional outcome following bone transport reconstruction of distal tibial defects.

Authors:  Konstantinos A Giannikas; Constantinos N Maganaris; Michael T Karski; Peter Twigg; Richard A Wilkes; John G Buckley
Journal:  J Bone Joint Surg Am       Date:  2005-01       Impact factor: 5.284

Review 4.  Induced membranes--a staged technique of bone-grafting for segmental bone loss: a report of two cases and a literature review.

Authors:  Colin Yi-Loong Woon; Keen-Wai Chong; Merng-Koon Wong
Journal:  J Bone Joint Surg Am       Date:  2010-01       Impact factor: 5.284

5.  Using the bi-masquelet technique and reamer-irrigator-aspirator for post-traumatic foot reconstruction.

Authors:  Lanie K Huffman; John G Harris; Michael Suk
Journal:  Foot Ankle Int       Date:  2009-09       Impact factor: 2.827

6.  Treatment of large segmental bone defects with reamer-irrigator-aspirator bone graft: technique and case series.

Authors:  Todd A McCall; David S Brokaw; Bradley A Jelen; D Kevin Scheid; Angela V Scharfenberger; Dean C Maar; James M Green; Melanie R Shipps; Marcus B Stone; Dana Musapatika; Timothy G Weber
Journal:  Orthop Clin North Am       Date:  2010-01       Impact factor: 2.472

Review 7.  The concept of induced membrane for reconstruction of long bone defects.

Authors:  Alain C Masquelet; Thierry Begue
Journal:  Orthop Clin North Am       Date:  2010-01       Impact factor: 2.472

Review 8.  Limb-lengthening, skeletal reconstruction, and bone transport with the Ilizarov method.

Authors:  J Aronson
Journal:  J Bone Joint Surg Am       Date:  1997-08       Impact factor: 5.284

9.  Non-vascularised fibular transfer in the management of defects of long bones after sequestrectomy in children.

Authors:  C W B Steinlechner; N C Mkandawire
Journal:  J Bone Joint Surg Br       Date:  2005-09

10.  Two-stage reconstruction of post-traumatic segmental tibia bone loss with nailing.

Authors:  T Apard; N Bigorre; P Cronier; F Duteille; P Bizot; P Massin
Journal:  Orthop Traumatol Surg Res       Date:  2010-06-04       Impact factor: 2.256

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  5 in total

1.  Induced membrane maintains its osteogenic properties even when the second stage of Masquelet's technique is performed later.

Authors:  Florelle Gindraux; François Loisel; Michael Bourgeois; Karim Oudina; Martine Melin; Benoit de Billy; Pauline Sergent; Gregoire Leclerc; Hervé Petite; Frederic Auber; Laurent Obert; Isabelle Pluvy
Journal:  Eur J Trauma Emerg Surg       Date:  2019-07-18       Impact factor: 3.693

2.  Union, complication, reintervention and failure rates of surgical techniques for large diaphyseal defects: a systematic review and meta-analysis.

Authors:  Pietro Feltri; Luca Solaro; Alessandro Di Martino; Christian Candrian; Costantino Errani; Giuseppe Filardo
Journal:  Sci Rep       Date:  2022-06-01       Impact factor: 4.996

3.  A Three-Dimensional Printed Polycaprolactone Scaffold Combined with Co-Axially Electrospun Vancomycin/Ceftazidime/Bone Morphological Protein-2 Sheath-Core Nanofibers for the Repair of Segmental Bone Defects During the Masquelet Procedure.

Authors:  Yi-Hsun Yu; Demei Lee; Yung-Heng Hsu; Ying-Chao Chou; Steve Wn Ueng; Che-Kang Chen; Shih-Jung Liu
Journal:  Int J Nanomedicine       Date:  2020-02-11

4.  The Induced Membrane Technique for the Management of Segmental Tibial Defect or Nonunion: A Systematic Review and Meta-Analysis.

Authors:  Chen-An Hsu; Shih-Heng Chen; Soa-Yu Chan; Yi-Hsun Yu
Journal:  Biomed Res Int       Date:  2020-05-22       Impact factor: 3.411

5.  Ilizarov bone transport combined with the Masquelet technique for bone defects of various etiologies (preliminary results).

Authors:  Dmitry Y Borzunov; Sergey N Kolchin; Denis S Mokhovikov; Tatiana A Malkova
Journal:  World J Orthop       Date:  2022-03-18
  5 in total

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