Literature DB >> 19005621

Enhanced production of poly (gamma-glutamic acid) from Bacillus licheniformis NCIM 2324 by using metabolic precursors.

Ishwar B Bajaj1, Rekha S Singhal.   

Abstract

The aim of the present work was to study the effect of addition of different amino acids and tricarboxylic acid cycle intermediates as metabolic precursors on the production of poly (gamma-glutamic acid) (PGA) by Bacillus licheniformis NCIM 2324. A maximum yield of 35.75 g/l was obtained with the medium supplemented with 0.5 mM L-glutamine and 10 mM alpha-ketoglutaric acid as compared to 26.12 g/l PGA achieved with the control in the absence of metabolic precursors. Addition of precursors also enhanced the utilization of L-glutamic acid during fermentation.

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Year:  2008        PMID: 19005621     DOI: 10.1007/s12010-008-8427-5

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN: 0273-2289            Impact factor:   2.926


  12 in total

1.  Factors increasing poly-γ-glutamic acid content of cheongguk-jang fermented by Bacillus subtilis 168.

Authors:  Pov Ratha; Deok-Young Jhon
Journal:  Food Sci Biotechnol       Date:  2018-07-11       Impact factor: 2.391

Review 2.  Microbial production of poly-γ-glutamic acid.

Authors:  Sarote Sirisansaneeyakul; Mingfeng Cao; Nuttawut Kongklom; Chaniga Chuensangjun; Zhongping Shi; Yusuf Chisti
Journal:  World J Microbiol Biotechnol       Date:  2017-09-05       Impact factor: 3.312

3.  Structural and genetic insights into a poly-γ-glutamic acid with in vitro antioxidant activity of Bacillus velezensis VCN56.

Authors:  Ngoc Tung Quach; Thi Hanh Nguyen Vu; Thi Thu An Nguyen; Hoang Ha; Phu-Ha Ho; Son Chu-Ky; Lan-Huong Nguyen; Hai Van Nguyen; Thi Thu Thuy Thanh; Ngoc Anh Nguyen; Hoang Ha Chu; Quyet-Tien Phi
Journal:  World J Microbiol Biotechnol       Date:  2022-08-03       Impact factor: 4.253

Review 4.  Genetic and metabolic engineering for poly-γ-glutamic acid production: current progress, challenges, and prospects.

Authors:  Zheng Zhang; Penghui He; Dongbo Cai; Shouwen Chen
Journal:  World J Microbiol Biotechnol       Date:  2022-08-28       Impact factor: 4.253

5.  Effects of metabolic pathway precursors and polydimethylsiloxane (PDMS) on poly-(gamma)-glutamic acid production by Bacillus subtilis BL53.

Authors:  Alessandra de Cesaro; Suse Botelho da Silva; Marco Antônio Záchia Ayub
Journal:  J Ind Microbiol Biotechnol       Date:  2014-07-11       Impact factor: 3.346

6.  Metabolic engineering of Bacillus amyloliquefaciens for poly-gamma-glutamic acid (γ-PGA) overproduction.

Authors:  Jun Feng; Yanyan Gu; Yang Sun; Lifang Han; Chao Yang; Wei Zhang; Mingfeng Cao; Cunjiang Song; Weixia Gao; Shufang Wang
Journal:  Microb Biotechnol       Date:  2014-07-01       Impact factor: 5.813

7.  Stimulatory effects of amino acids on γ-polyglutamic acid production by Bacillus subtilis.

Authors:  Chao Zhang; Daoji Wu; Xueliang Qiu
Journal:  Sci Rep       Date:  2018-12-18       Impact factor: 4.379

8.  Improved production of melanin from Aspergillus fumigatus AFGRD105 by optimization of media factors.

Authors:  Nitya Meenakshi Raman; Pooja Harish Shah; Misha Mohan; Suganthi Ramasamy
Journal:  AMB Express       Date:  2015-11-24       Impact factor: 3.298

Review 9.  Microbial synthesis of poly-γ-glutamic acid: current progress, challenges, and future perspectives.

Authors:  Zhiting Luo; Yuan Guo; Jidong Liu; Hua Qiu; Mouming Zhao; Wei Zou; Shubo Li
Journal:  Biotechnol Biofuels       Date:  2016-06-29       Impact factor: 6.040

Review 10.  Poly-γ-glutamic Acid Synthesis, Gene Regulation, Phylogenetic Relationships, and Role in Fermentation.

Authors:  Yi-Huang Hsueh; Kai-Yao Huang; Sikhumbuzo Charles Kunene; Tzong-Yi Lee
Journal:  Int J Mol Sci       Date:  2017-12-07       Impact factor: 5.923

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