Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet.

Literature DB >> 18956044

Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet.

Pinpin Sheng¹, Zunyi Yang, Youngmi Kim, Yanrong Wu, Weihong Tan, Steven A Benner.

Abstract

A molecular beacon that incorporates components of an artificially expanded genetic information system (Aegis) in its stem is shown not to be opened by unwanted stem invasion by adventitious standard DNA; this should improve the "darkness" of the beacon in real-world applications.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2008 PMID： 18956044 PMCID： PMC2763601 DOI： 10.1039/b811159f

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

15 in total

1. Molecular Beacons: A Novel Approach to Detect Protein - DNA Interactions This work was partially supported by a U.S. NSF Career Award (CHE-9733650) and by a U.S. Office of Naval Research Young Investigator Award (N00014-98-1-0621).

Authors:
Journal: Angew Chem Int Ed Engl Date: 2000-03 Impact factor: 15.336

Review 2. Molecular beacons: a novel DNA probe for nucleic acid and protein studies.

Authors: W Tan; X Fang; J Li; X Liu
Journal: Chemistry Date: 2000-04-03 Impact factor: 5.236

3. Use of DNA and peptide nucleic acid molecular beacons for detection and quantification of rRNA in solution and in whole cells.

Authors: Chuanwu Xi; Michal Balberg; Stephen A Boppart; Lutgarde Raskin
Journal: Appl Environ Microbiol Date: 2003-09 Impact factor: 4.792

4. Locked nucleic acid molecular beacons.

Authors: Lin Wang; Chaoyong James Yang; Colin D Medley; Steven A Benner; Weihong Tan
Journal: J Am Chem Soc Date: 2005-11-16 Impact factor: 15.419

5. Molecular beacons: probes that fluoresce upon hybridization.

Authors: S Tyagi; F R Kramer
Journal: Nat Biotechnol Date: 1996-03 Impact factor: 54.908

Review 6. Understanding nucleic acids using synthetic chemistry.

Authors: Steven A Benner
Journal: Acc Chem Res Date: 2004-10 Impact factor: 22.384

7. Multicenter evaluation of the performance characteristics of the bayer VERSANT HCV RNA 3.0 assay (bDNA).

Authors: Tarek Elbeik; Johan Surtihadi; Mark Destree; Jed Gorlin; Mark Holodniy; Saeed A Jortani; Ken Kuramoto; Valerie Ng; Roland Valdes; Alexandra Valsamakis; Norah A Terrault
Journal: J Clin Microbiol Date: 2004-02 Impact factor: 5.948

8. tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells.

Authors: Musa M Mhlanga; Diana Y Vargas; Cindy W Fung; Fred Russell Kramer; Sanjay Tyagi
Journal: Nucleic Acids Res Date: 2005-04-04 Impact factor: 16.971

9. Molecular beacons with a homo-DNA stem: improving target selectivity.

Authors: Caroline Crey-Desbiolles; Dae-Ro Ahn; Christian J Leumann
Journal: Nucleic Acids Res Date: 2005-05-05 Impact factor: 16.971

10. Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern.

Authors: Zunyi Yang; Daniel Hutter; Pinpin Sheng; A Michael Sismour; Steven A Benner
Journal: Nucleic Acids Res Date: 2006-10-29 Impact factor: 16.971

11 in total

1. Engineering of Bioinspired, Size-Controllable, Self-Degradable Cancer-Targeting DNA Nanoflowers via the Incorporation of an Artificial Sandwich Base.

Authors: Lili Zhang; Razack Abdullah; Xiaoxiao Hu; Huarong Bai; Huanhuan Fan; Lei He; Hao Liang; Jianmei Zou; Yanlan Liu; Yang Sun; Xiaobing Zhang; Weihong Tan
Journal: J Am Chem Soc Date: 2019-03-05 Impact factor: 15.419

Review 2. Rationally designed molecular beacons for bioanalytical and biomedical applications.

Authors: Jing Zheng; Ronghua Yang; Muling Shi; Cuichen Wu; Xiaohong Fang; Yinhui Li; Jishan Li; Weihong Tan
Journal: Chem Soc Rev Date: 2015-03-17 Impact factor: 54.564

3. Expanded genetic alphabets in the polymerase chain reaction.

Authors: Zunyi Yang; Fei Chen; Stephen G Chamberlin; Steven A Benner
Journal: Angew Chem Int Ed Engl Date: 2010 Impact factor: 15.336

4. An Aptamer-Nanotrain Assembled from Six-Letter DNA Delivers Doxorubicin Selectively to Liver Cancer Cells.

Authors: Liqin Zhang; Sai Wang; Zunyi Yang; Shuichi Hoshika; Sitao Xie; Jin Li; Xigao Chen; Shuo Wan; Long Li; Steven A Benner; Weihong Tan
Journal: Angew Chem Int Ed Engl Date: 2019-11-19 Impact factor: 15.336

5. Fluorinated molecular beacons as functional DNA nanomolecules for cellular imaging.

Authors: Cheng Jin; Ting Fu; Ruowen Wang; Hui Liu; Jianmei Zou; Zilong Zhao; Mao Ye; Xiaobing Zhang; Weihong Tan
Journal: Chem Sci Date: 2017-08-21 Impact factor: 9.825

6. Engineering molecular beacons for intracellular imaging.

Authors: Cuichen Sam Wu; Lu Peng; Mingxu You; Da Han; Tao Chen; Kathryn R Williams; Chaoyong James Yang; Weihong Tan
Journal: Int J Mol Imaging Date: 2012-11-06

Review 7. An elegant biosensor molecular beacon probe: challenges and recent solutions.

Authors: Dmitry M Kolpashchikov
Journal: Scientifica (Cairo) Date: 2012-12-13

8. Standard and AEGIS nicking molecular beacons detect amplicons from the Middle East respiratory syndrome coronavirus.

Authors: Ozlem Yaren; Lyudmyla G Glushakova; Kevin M Bradley; Shuichi Hoshika; Steven A Benner
Journal: J Virol Methods Date: 2016-07-12 Impact factor: 2.014

9. Modified nucleotides may have enhanced early RNA catalysis.

Authors: Steven K Wolk; Wesley S Mayfield; Amy D Gelinas; David Astling; Jessica Guillot; Edward N Brody; Nebojsa Janjic; Larry Gold
Journal: Proc Natl Acad Sci U S A Date: 2020-03-30 Impact factor: 11.205

10. Molecular domino reactor built by automated modular synthesis for cancer treatment.

Authors: Yu Yang; Jiaxuan He; Wenjun Zhu; Xiaoshu Pan; Hoda Safari Yazd; Cheng Cui; Lu Yang; Xiaowei Li; Long Li; Liang Cheng; Liangzhu Feng; Ruowen Wang; Zhuang Liu; Meiwan Chen; Weihong Tan
Journal: Theranostics Date: 2020-03-04 Impact factor: 11.556