Literature DB >> 1895326

Comparison of a DNA probe assay with culture for the detection of Chlamydia trachomatis.

M I Lees1, D M Newnan, S M Garland.   

Abstract

A new DNA probe assay (PACE 2, Gen-probe) was compared with cell culture for the detection of Chlamydia trachomatis in 909 women attending the Royal Women's Hospital, Melbourne, Victoria. The DNA probe assay had a sensitivity of 86.2%, a specificity of 99.9% and a positive predictive value of 96.2% in a population with 3.2% prevalence, indicating that it may be a suitable alternative to culture for the detection of C. trachomatis in specimens from the genital tract.

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Year:  1991        PMID： 1895326     DOI： 10.1099/00222615-35-3-159

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN： 0022-2615            Impact factor:   2.472


  8 in total

1.  The value of non-culture techniques for diagnosis of Chlamydia trachomatis infections: making the best of a bad job.

Authors:  D Taylor-Robinson
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-06       Impact factor: 3.267

2.  "Shotgun" versus sequential testing. Cost-effectiveness of diagnostic strategies for vaginitis.

Authors:  Phyllis L Carr; Michael B Rothberg; Robert H Friedman; Donna Felsenstein; Joseph S Pliskin
Journal:  J Gen Intern Med       Date:  2005-09       Impact factor: 5.128

Review 3.  Current methods of laboratory diagnosis of Chlamydia trachomatis infections.

Authors:  C M Black
Journal:  Clin Microbiol Rev       Date:  1997-01       Impact factor: 26.132

4.  Comparison of the Syva MicroTrak enzyme immunoassay and Gen-Probe PACE 2 with cell culture for diagnosis of cervical Chlamydia trachomatis infection in a high-prevalence female population.

Authors:  L M Clarke; M F Sierra; B J Daidone; N Lopez; J M Covino; W M McCormack
Journal:  J Clin Microbiol       Date:  1993-04       Impact factor: 5.948

5.  Detection of Chlamydia trachomatis in urethral and urine samples from symptomatic and asymptomatic male patients by the polymerase chain reaction.

Authors:  A Stary; B Choueiri; I Hörting-Müller; P Halisch; L Teodorowicz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1996-06       Impact factor: 3.267

6.  Comparative evaluation of detection assays for Chlamydia trachomatis.

Authors:  R Warren; B Dwyer; M Plackett; K Pettit; N Rizvi; A M Baker
Journal:  J Clin Microbiol       Date:  1993-06       Impact factor: 5.948

7.  Rapid detection of Streptococcus pyogenes in pediatric patient specimens by DNA probe.

Authors:  L L Steed; E K Korgenski; J A Daly
Journal:  J Clin Microbiol       Date:  1993-11       Impact factor: 5.948

8.  Infection with a plasmid-free variant Chlamydia related to Chlamydia trachomatis identified by using multiple assays for nucleic acid detection.

Authors:  Q An; G Radcliffe; R Vassallo; D Buxton; W J O'Brien; D A Pelletier; W G Weisburg; J D Klinger; D M Olive
Journal:  J Clin Microbiol       Date:  1992-11       Impact factor: 5.948
  8 in total

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