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Literature DB >> 18941819

Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp.

Hyi-Seung Lee¹, Ji Hye Lee, Hoshik Won, Song-Kyu Park, Hwan Mook Kim, Hee Jae Shin, Heung Sik Park, Chung J Sim, Hye-Kyeong Kim.

Abstract

Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont-(4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyran-4-one (3). The acetylenic alcohol (1) exhibited significant growth inhibitory effect against human tumor cell lines.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2008 PMID： 18941819 DOI： 10.1007/s11745-008-3249-3

Source DB: PubMed Journal: Lipids ISSN： 0024-4201 Impact factor: 1.880

17 in total

1. Callyspongynes A and B: new polyacetylenic lipids from a southern Australian marine sponge, Callyspongia sp.

Authors: F Rooney; R J Capon
Journal: Lipids Date: 1998-06 Impact factor: 1.880

2. Antitumor activity and stereochemistry of acetylenic alcohols from the sponge Cribrochalina vasculum.

Authors: Y F Hallock; J H Cardellina; M S Balaschak; M R Alexander; T R Prather; R H Shoemaker; M R Boyd
Journal: J Nat Prod Date: 1995-12 Impact factor: 4.050

Review 3. Anticancer activity of natural and synthetic acetylenic lipids.

Authors: Valery M Dembitsky
Journal: Lipids Date: 2006-10 Impact factor: 1.880

4. Triangulynes A-H and trangulynic acid, new cytotxic polyacetylenes from the marine sponge Pellina triangulata.

Authors: J R Dai; Y F Hallock; I I Cardellina JH; G N Gray; M R Boyd
Journal: J Nat Prod Date: 1996-09 Impact factor: 4.050

5. Sesterterpene sulfates as isocitrate lyase inhibitors from tropical sponge Hippospongia sp.

Authors: Hyi-Seung Lee; Tae-Hoon Lee; Seung Hwan Yang; Hee Jae Shin; Jongheon Shin; Ki-Bong Oh
Journal: Bioorg Med Chem Lett Date: 2007-02-13 Impact factor: 2.823

6. Additional cytotoxic polyacetylenes from the marine sponge Petrosia species.

Authors: Y J Lim; H S Park; K S Im; C Lee; J Hong; M Lee; D Kim Dk; J H Jung
Journal: J Nat Prod Date: 2001-01 Impact factor: 4.050

7. Acetylenic strongylodiols from a Petrosia (Strongylophora) Okinawan marine sponge.

Authors: Kinzo Watanabe; Yuichiro Tsuda; Maki Hamada; Miki Omori; Go Mori; Kazuo Iguchi; Hideo Naoki; Tsuyoshi Fujita; Rob W M Van Soest
Journal: J Nat Prod Date: 2005-07 Impact factor: 4.050

8. Callyspongenols A-C, new cytotoxic C22-polyacetylenic alcohols from a red sea sponge, Callyspongia species.

Authors: Diaa T A Youssef; Rob W M van Soest; Nobuhiro Fusetani
Journal: J Nat Prod Date: 2003-05 Impact factor: 4.050

9. Callyspongynic acid, a polyacetylenic acid which inhibits alpha-glucosidase, from the marine sponge Callyspongia truncata.

Authors: Yoichi Nakao; Taisuke Uehara; Shigeki Matsunaga; Nobuhiro Fusetani; Rob W M van Soest; Shigeki Matunaga
Journal: J Nat Prod Date: 2002-06 Impact factor: 4.050