Literature DB >> 12762806

Callyspongenols A-C, new cytotoxic C22-polyacetylenic alcohols from a red sea sponge, Callyspongia species.

Diaa T A Youssef1, Rob W M van Soest, Nobuhiro Fusetani.   

Abstract

Investigation of the organic extract of a Red Sea sponge, Callyspongia sp., resulted in isolation and identification of three new C(22)-polyacetylenic alcohols, callyspongenols A-C (1-3), together with dehydroisophonochalynol (4). The structures of 1-3 were determined by 1D and 2D NMR studies and mass spectral determinations. Compounds 1-4 showed moderate cytotoxicity against P388 and HeLa cells.

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Year:  2003        PMID: 12762806     DOI: 10.1021/np030006c

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

Review 1.  Anticancer activity of natural and synthetic acetylenic lipids.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-10       Impact factor: 1.880

2.  Callyspongiolide, a cytotoxic macrolide from the marine sponge Callyspongia sp.

Authors:  Cong-Dat Pham; Rudolf Hartmann; Philip Böhler; Björn Stork; Sebastian Wesselborg; Wenhan Lin; Daowan Lai; Peter Proksch
Journal:  Org Lett       Date:  2013-12-13       Impact factor: 6.005

Review 3.  Biosynthesis and function of polyacetylenes and allied natural products.

Authors:  Robert E Minto; Brenda J Blacklock
Journal:  Prog Lipid Res       Date:  2008-03-13       Impact factor: 16.195

4.  Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp.

Authors:  Hyi-Seung Lee; Ji Hye Lee; Hoshik Won; Song-Kyu Park; Hwan Mook Kim; Hee Jae Shin; Heung Sik Park; Chung J Sim; Hye-Kyeong Kim
Journal:  Lipids       Date:  2008-10-22       Impact factor: 1.880

Review 5.  Natural Products Repertoire of the Red Sea.

Authors:  Ebaa M El-Hossary; Mohammad Abdel-Halim; Eslam S Ibrahim; Sheila Marie Pimentel-Elardo; Justin R Nodwell; Heba Handoussa; Miada F Abdelwahab; Ulrike Holzgrabe; Usama Ramadan Abdelmohsen
Journal:  Mar Drugs       Date:  2020-09-04       Impact factor: 5.118

Review 6.  Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data.

Authors:  Lucas Hilário Nogueira de Sousa; Rusceli Diego de Araújo; Déborah Sousa-Fontoura; Fabrício Gava Menezes; Renata Mendonça Araújo
Journal:  Mar Drugs       Date:  2021-11-26       Impact factor: 5.118

  6 in total

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