Literature DB >> 17317180

Sesterterpene sulfates as isocitrate lyase inhibitors from tropical sponge Hippospongia sp.

Hyi-Seung Lee1, Tae-Hoon Lee, Seung Hwan Yang, Hee Jae Shin, Jongheon Shin, Ki-Bong Oh.   

Abstract

Two sesterterpene sulfates (1-2) were isolated from tropical sponge Hippospongia sp. and their inhibitory activities against isocitrate lyase (ICL) from the rice blast fungus Mgnaporthe grisea were evaluated. Compound 3 was obtained by hydrolysis of compound 1. Compounds 1 and 3 were found to be potent ICL inhibitors, which inhibited appressorium formation and C(2) carbon utilization in M. grisea. Our results suggest that ICL plays crucial role in appressorium formation of M. grisea and is a new target for the protection of rice blast disease.

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Year:  2007        PMID： 17317180     DOI： 10.1016/j.bmcl.2007.02.027

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  10 in total

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Authors:  Xiuyun Li; Yinglong Hou; Longtao Yue; Shuyuan Liu; Juan Du; Shujuan Sun
Journal:  Antimicrob Agents Chemother       Date:  2015-07-20       Impact factor: 5.191

2.  Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp.

Authors:  Hyi-Seung Lee; Ji Hye Lee; Hoshik Won; Song-Kyu Park; Hwan Mook Kim; Hee Jae Shin; Heung Sik Park; Chung J Sim; Hye-Kyeong Kim
Journal:  Lipids       Date:  2008-10-22       Impact factor: 1.880

3.  Cytotoxic sesterterpenoids from a sponge Hippospongia sp.

Authors:  Yu-Chia Chang; Shang-Wei Tseng; Li-Lian Liu; Yalan Chou; Yuan-Shing Ho; Mei-Chin Lu; Jui-Hsin Su
Journal:  Mar Drugs       Date:  2012-04-27       Impact factor: 6.085

4.  Lumazine peptides from the marine-derived fungus Aspergillus terreus.

Authors:  Minjung You; Lijuan Liao; Soo Hyun Hong; Wanki Park; Dah In Kwon; Jeeyeon Lee; Minsoo Noh; Dong-Chan Oh; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2015-03-12       Impact factor: 5.118

5.  Bioactive Bianthraquinones and Meroterpenoids from a Marine-Derived Stemphylium sp. Fungus.

Authors:  Ji-Yeon Hwang; Sung Chul Park; Woong Sub Byun; Dong-Chan Oh; Sang Kook Lee; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2020-08-21       Impact factor: 5.118

6.  Ochraceopetalin, a Mixed-Biogenetic Salt of Polyketide and Amino Acid Origins from a Marine-Derived Aspergillus ochraceopetaliformis Fungus.

Authors:  Sung Chul Park; Jung-Ho Lee; Ji-Yeon Hwang; Oh-Seok Kwon; Lijuan Liao; Dong-Chan Oh; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2021-07-26       Impact factor: 5.118

7.  Cyclic Bis-1,3-dialkylpyridiniums from the sponge Haliclona sp.

Authors:  Yoonyeong Lee; Kyoung Hwa Jang; Ju-Eun Jeon; Woo-Young Yang; Chung J Sim; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2012-09-24       Impact factor: 6.085

Review 8.  Meroterpenes from marine invertebrates: structures, occurrence, and ecological implications.

Authors:  Marialuisa Menna; Concetta Imperatore; Filomena D'Aniello; Anna Aiello
Journal:  Mar Drugs       Date:  2013-05-17       Impact factor: 5.118

Review 9.  Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary.

Authors:  Yie-Vern Lee; Habibah A Wahab; Yee Siew Choong
Journal:  Biomed Res Int       Date:  2015-01-08       Impact factor: 3.411

10.  New hippolide derivatives with protein tyrosine phosphatase 1B inhibitory activity from the marine sponge Hippospongia lachne.

Authors:  Shu-Juan Piao; Wei-Hua Jiao; Fan Yang; Yang-Hua Yi; Ying-Tong Di; Bing-Nan Han; Hou-Wen Lin
Journal:  Mar Drugs       Date:  2014-07-08       Impact factor: 5.118
  10 in total

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