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Literature DB >> 188680

Inhibition in the rat of gastric acid secretion and cyclic AMP analogs accumulation in vitro by somatostatin.

Abstract

Various somatostatin (S) analogs exhibited similar degree and similar, or shorter, duration of inhibition of basal gastric acid secretion as S in the unanesthetized rat and similar, or less, inhibition of the cyclic AMP accumulation induced by prostaglandin E2 in the rat anterior pituitary in vitro. With the analogs examined, the gastrointestinal and pituitary receptors appear to exhibit generally similar recognition specificity with the differences within the gastro-intestinal activities reflecting duration of availability rather than receptor affinity.

Entities: Chemical Disease Species

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Year: 1977 PMID： 188680 DOI： 10.1007/bf01936755

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

12 in total

1. Inhibition of gastric acid secretion by somatostatin and analogs in the rat.

Authors: W Lippmann; L E Borella
Journal: Pharmacol Res Commun Date: 1976-10

2. Synthesis of somatostatin.

Authors: H U Immer; K Sestanj; V R Nelson; M Götz
Journal: Helv Chim Acta Date: 1974-04-27 Impact factor: 2.164

3. Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone.

Authors: P Borgeat; F Labrie; J Drouin; A Bélanger; H Immer; K Sestanj; V Nelson; M Götz; A V Schally; D H Coy; E J Coy
Journal: Biochem Biophys Res Commun Date: 1974-02-27 Impact factor: 3.575

4. In vitro effects of synthetic somatotropin-release inhibiting factor on cyclic AMP level and GH release in rat anterior pituitary gland.

Authors: T Kaneko; H Oka; S Saito; M Munemura; K Musa; T Oda
Journal: Endocrinol Jpn Date: 1973-10

5. Actinomycin-insensitive stimulation of protein synthesis in rat anterior pituitary in vitro by dibutyryl adenosine 3',5'-monophosphate.

Authors: F Labrie; G Béraud; M Gauthier; A Lemay
Journal: J Biol Chem Date: 1971-03-25 Impact factor: 5.157

9. Stimulation of adenosine 3':5'-cyclic monophosphate accumulation in anterior pituitary gland in vitro by synthetic luteinizing hormone-releasing hormone.

Authors: P Borgeat; G Chavancy; A Dupont; F Labrie; A Arimura; A V Schally
Journal: Proc Natl Acad Sci U S A Date: 1972-09 Impact factor: 11.205

10. Antagonism of prostaglandin-induced cyclic AMP accumulation in the rat anterior pituitary in vitro by somatostatin analogues.

Authors: W Lippmann; K Sestanj; V R Nelson; H U Immer
Journal: Experientia Date: 1976-08-15

1 in total

1. Inhibition of prostaglandin-induced cyclic AMP accumulation in the rat anterior pituitary by alrestatin.

Authors: W Lippmann
Journal: Experientia Date: 1978-04-15