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Literature DB >> 182523

Antagonism of prostaglandin-induced cyclic AMP accumulation in the rat anterior pituitary in vitro by somatostatin analogues.

W Lippmann, K Sestanj, V R Nelson, H U Immer.

Abstract

The PGE2-induced cyclic AMP accumulation in the rat anterior pituitary in vitro is inhibited by [desamino1]-[desamino1] [descarboxy14]- and [D-Lys4]-somatostatin similarly to somatostatin, while the [descarboxy14]-somatostatin exhibits reduced activity; [D-Lys9]-somatostatin is ineffective at a higher concentration.

Entities: Chemical Species

Mesh：

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Year: 1976 PMID： 182523 DOI： 10.1007/bf01933956

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

18 in total

1. Synthesis of somatostatin.

Authors: H U Immer; K Sestanj; V R Nelson; M Götz
Journal: Helv Chim Acta Date: 1974-04-27 Impact factor: 2.164

2. Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone.

Authors: P Borgeat; F Labrie; J Drouin; A Bélanger; H Immer; K Sestanj; V Nelson; M Götz; A V Schally; D H Coy; E J Coy
Journal: Biochem Biophys Res Commun Date: 1974-02-27 Impact factor: 3.575

3. In vitro effects of synthetic somatotropin-release inhibiting factor on cyclic AMP level and GH release in rat anterior pituitary gland.

Authors: T Kaneko; H Oka; S Saito; M Munemura; K Musa; T Oda
Journal: Endocrinol Jpn Date: 1973-10

4. Antagonism of prostaglandin-promoted pituitary cyclic AMP accumulation and growth hormone secretion in vitro by 7-oxa-13-prostynoic acid.

Authors: A Ratner; M C Wilson; G T Peake
Journal: Prostaglandins Date: 1973-04

5. [Preliminary observations on the mechanism of action of somatostatin, a hypothalamic factor inhibiting the secretion of growth hormone].

Authors: W Vale; P Brazeau; G Grant; A Nussey; R Burgus; J Rivier; N Ling; R Guillemin
Journal: C R Acad Hebd Seances Acad Sci D Date: 1972-12-18

6. Studies on growth hormone secretion. II. Stimulation by prostaglandins in vitro.

Authors: F Hertelendy
Journal: Acta Endocrinol (Copenh) Date: 1971-10

7. Studies on growth hormone secretion. 3. Inhibition of prostaglandin, theophylline and cyclic amp stimulated growth hormone release by valinomycin in vitro.

Authors: F Hertelendy; G Peake; H Todd
Journal: Biochem Biophys Res Commun Date: 1971-07-16 Impact factor: 3.575

8. Actinomycin-insensitive stimulation of protein synthesis in rat anterior pituitary in vitro by dibutyryl adenosine 3',5'-monophosphate.

Authors: F Labrie; G Béraud; M Gauthier; A Lemay
Journal: J Biol Chem Date: 1971-03-25 Impact factor: 5.157

9. Stimulation of adenosine 3':5'-cyclic monophosphate accumulation in anterior pituitary gland in vitro by synthetic luteinizing hormone-releasing hormone.

Authors: P Borgeat; G Chavancy; A Dupont; F Labrie; A Arimura; A V Schally
Journal: Proc Natl Acad Sci U S A Date: 1972-09 Impact factor: 11.205

10. The effect of prostaglandins on ox pituitary content of adenosine 3':5'-cyclic monophosphate and the release of growth hormone.

Authors: R H Cooper; M McPherson; J G Schofield
Journal: Biochem J Date: 1972-03 Impact factor: 3.857

3 in total