OBJECTIVE: To compare pressure-volume (P-V) curves obtained with the Galileo ventilator with those obtained with the CPAP method in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). DESIGN: Prospective, observational study. SETTING: General critical care center. PATIENTS AND PARTICIPANTS: Patients with ALI/ARDS and receiving mechanical ventilation. INTERVENTIONS: Pressure-volume curves were obtained in random order with the CPAP technique and with the software PV Tool-2 (Galileo ventilator). MEASUREMENTS AND RESULTS: In ten consecutive patients, airway pressure was measured by a pressure transducer and changes in lung volume were measured by respiratory inductive plethysmography. P-V curves were fitted to a sigmoidal equation with a mean R (2) of 0.994 +/- 0.003. Intraclass correlation coefficients were all >0.75 (P < 0.001 at all pressure levels). Lower (LIP) and upper inflection (UIP), and deflation maximum curvature (PMC) points calculated from the fitted variables showed a good correlation between methods with intraclass correlation coefficients of 0.98 (0.92, 0.99), 0.92 (0.69, 0.98), and 0.97 (0.86, 0.98), respectively (P < 0.001 in all cases). Bias and limits of agreement for LIP (0.51 +/- 0.95 cmH(2)O; -1.36 to 2.38 cmH(2)O), UIP (0.53 +/- 1.52 cmH(2)O; -2.44 to 3.50 cmH(2)O), and PMC (-0.62 +/- 0.89 cmH(2)O; -2.35 to 1.12 cmH(2)O) obtained with the two methods in the same patient were clinically acceptable. No adverse effects were observed. CONCLUSION: The PV Tool-2 built into the Galileo ventilator is equivalent to the CPAP method for tracing static P-V curves of the respiratory system in critically ill patients receiving mechanical ventilation.
OBJECTIVE: To compare pressure-volume (P-V) curves obtained with the Galileo ventilator with those obtained with the CPAP method in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). DESIGN: Prospective, observational study. SETTING: General critical care center. PATIENTS AND PARTICIPANTS: Patients with ALI/ARDS and receiving mechanical ventilation. INTERVENTIONS: Pressure-volume curves were obtained in random order with the CPAP technique and with the software PV Tool-2 (Galileo ventilator). MEASUREMENTS AND RESULTS: In ten consecutive patients, airway pressure was measured by a pressure transducer and changes in lung volume were measured by respiratory inductive plethysmography. P-V curves were fitted to a sigmoidal equation with a mean R (2) of 0.994 +/- 0.003. Intraclass correlation coefficients were all >0.75 (P < 0.001 at all pressure levels). Lower (LIP) and upper inflection (UIP), and deflation maximum curvature (PMC) points calculated from the fitted variables showed a good correlation between methods with intraclass correlation coefficients of 0.98 (0.92, 0.99), 0.92 (0.69, 0.98), and 0.97 (0.86, 0.98), respectively (P < 0.001 in all cases). Bias and limits of agreement for LIP (0.51 +/- 0.95 cmH(2)O; -1.36 to 2.38 cmH(2)O), UIP (0.53 +/- 1.52 cmH(2)O; -2.44 to 3.50 cmH(2)O), and PMC (-0.62 +/- 0.89 cmH(2)O; -2.35 to 1.12 cmH(2)O) obtained with the two methods in the same patient were clinically acceptable. No adverse effects were observed. CONCLUSION: The PV Tool-2 built into the Galileo ventilator is equivalent to the CPAP method for tracing static P-V curves of the respiratory system in critically illpatients receiving mechanical ventilation.
Authors: Frédérique Bayle; Claude Guérin; Sophie Debord; Michel Badet; Stéphane Lemasson; Jean-Charles Poupelin; Jean-Christophe Richard Journal: Intensive Care Med Date: 2006-04-07 Impact factor: 17.440
Authors: G R Bernard; A Artigas; K L Brigham; J Carlet; K Falke; L Hudson; M Lamy; J R Legall; A Morris; R Spragg Journal: Am J Respir Crit Care Med Date: 1994-03 Impact factor: 21.405
Authors: Q Lu; S R Vieira; J Richecoeur; L Puybasset; P Kalfon; P Coriat; J J Rouby Journal: Am J Respir Crit Care Med Date: 1999-01 Impact factor: 21.405
Authors: Guillermo M Albaiceta; Luis H Luyando; Diego Parra; Rafael Menendez; Juan Calvo; Paula Rodríguez Pedreira; Francisco Taboada Journal: Intensive Care Med Date: 2005-08-10 Impact factor: 17.440
Authors: Pier Paolo Terragni; Giulio Rosboch; Andrea Tealdi; Eleonora Corno; Eleonora Menaldo; Ottavio Davini; Giovanni Gandini; Peter Herrmann; Luciana Mascia; Michel Quintel; Arthur S Slutsky; Luciano Gattinoni; V Marco Ranieri Journal: Am J Respir Crit Care Med Date: 2006-10-12 Impact factor: 21.405
Authors: V M Ranieri; P M Suter; C Tortorella; R De Tullio; J M Dayer; A Brienza; F Bruno; A S Slutsky Journal: JAMA Date: 1999-07-07 Impact factor: 56.272
Authors: Massimo Antonelli; Elie Azoulay; Marc Bonten; Jean Chastre; Giuseppe Citerio; Giorgio Conti; Daniel De Backer; François Lemaire; Herwig Gerlach; Goran Hedenstierna; Michael Joannidis; Duncan Macrae; Jordi Mancebo; Salvatore M Maggiore; Alexandre Mebazaa; Jean-Charles Preiser; Jerôme Pugin; Jan Wernerman; Haibo Zhang Journal: Intensive Care Med Date: 2010-02-23 Impact factor: 17.440