Literature DB >> 18783406

Finding genes underlying human disease.

C M Stein1, R C Elston.   

Abstract

With the surge in genome-wide association studies (GWAS), many have asked the question 'Are linkage studies dead?' In this article, we survey the approaches used in mapping human disease genes, reviewing the analysis strategies that preceded and laid the groundwork for GWAS. We note that earlier approaches are still useful and the development of new methodology is warranted.

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Year:  2009        PMID： 18783406      PMCID： PMC3057167          DOI： 10.1111/j.1399-0004.2008.01083.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN： 0009-9163            Impact factor:   4.438


  53 in total

1.  Inference of population structure using multilocus genotype data.

Authors:  J K Pritchard; M Stephens; P Donnelly
Journal:  Genetics       Date:  2000-06       Impact factor: 4.562

2.  Genomic control for association studies.

Authors:  B Devlin; K Roeder
Journal:  Biometrics       Date:  1999-12       Impact factor: 2.571

3.  Assessment and implications of linkage disequilibrium in genome-wide single-nucleotide polymorphism and microsatellite panels.

Authors:  Ellen L Goode; Gail P Jarvik
Journal:  Genet Epidemiol       Date:  2005       Impact factor: 2.135

4.  Multipoint linkage analysis for a very dense set of markers.

Authors:  Silviu-Alin Bacanu
Journal:  Genet Epidemiol       Date:  2005-11       Impact factor: 2.135

5.  Regression-based multivariate linkage analysis with an application to blood pressure and body mass index.

Authors:  T Wang; R C Elston
Journal:  Ann Hum Genet       Date:  2007-01       Impact factor: 1.670

6.  Power calculations for likelihood ratio tests for offspring genotype risks, maternal effects, and parent-of-origin (POO) effects in the presence of missing parental genotypes when unaffected siblings are available.

Authors:  E Rampersaud; R W Morris; C R Weinberg; M C Speer; E R Martin
Journal:  Genet Epidemiol       Date:  2007-01       Impact factor: 2.135

7.  Linkage strategies for genetically complex traits. II. The power of affected relative pairs.

Authors:  N Risch
Journal:  Am J Hum Genet       Date:  1990-02       Impact factor: 11.025

8.  CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease.

Authors:  Suzanne Lesage; Habib Zouali; Jean-Pierre Cézard; Jean-Frédéric Colombel; Jacques Belaiche; Sven Almer; Curt Tysk; Colm O'Morain; Miquel Gassull; Vibeke Binder; Yigael Finkel; Robert Modigliani; Corinne Gower-Rousseau; Jeanne Macry; Françoise Merlin; Mathias Chamaillard; Anne-Sophie Jannot; Gilles Thomas; Jean-Pierre Hugot
Journal:  Am J Hum Genet       Date:  2002-03-01       Impact factor: 11.025

9.  A novel approach to detect parent-of-origin effects from pedigree data with application to Beckwith-Wiedemann syndrome.

Authors:  Sanjay Shete; Robert C Elston; Yue Lu
Journal:  Ann Hum Genet       Date:  2007-06-18       Impact factor: 1.670

Review 10.  Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Authors:  D Botstein; R L White; M Skolnick; R W Davis
Journal:  Am J Hum Genet       Date:  1980-05       Impact factor: 11.025
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  8 in total

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Authors:  Rosemarie Plaetke; Federico Balbi
Journal:  Bioinformatics       Date:  2010-09-15       Impact factor: 6.937

Review 2.  Genetic epidemiology of hip and knee osteoarthritis.

Authors:  Ana M Valdes; Tim D Spector
Journal:  Nat Rev Rheumatol       Date:  2010-11-16       Impact factor: 20.543

3.  Derived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases.

Authors:  Olga Y Gorlova; Jun Ying; Christopher I Amos; Margaret R Spitz; Bo Peng; Ivan P Gorlov
Journal:  J Bioinform Comput Biol       Date:  2012-04       Impact factor: 1.122

4.  Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants.

Authors:  Sandra E Branham; Sara J Wright; Aaron Reba; Ginnie D Morrison; C Randal Linder
Journal:  J Hered       Date:  2016-02-10       Impact factor: 2.645

5.  Genome-wide association mapping of flowering time in Arabidopsis thaliana in nature: genetics for underlying components and reaction norms across two successive years.

Authors:  Benjamin Brachi; Nathalie Faure; Joy Bergelson; Joël Cuguen; Fabrice Roux
Journal:  Acta Bot Gallica       Date:  2013-07-01

6.  PedWiz: a web-based tool for pedigree informatics.

Authors:  Yeunjoo E Song; Robert C Elston
Journal:  Front Genet       Date:  2013-09-25       Impact factor: 4.599

7.  Toll-like receptor 4 gene is associated with recurrent spontaneous miscarriage in Uygur and Han women in Xinjiang.

Authors:  Yonghui Jiao; Jing Zhao; Bo Hu; Xiaoling La; Xiaoyun Gong; Ying Huang; Xia Cai; Yi Zhang
Journal:  Exp Ther Med       Date:  2016-10-11       Impact factor: 2.447

8.  The household contact study design for genetic epidemiological studies of infectious diseases.

Authors:  Catherine M Stein; Noémi B Hall; Lashaunda L Malone; Ezekiel Mupere
Journal:  Front Genet       Date:  2013-04-30       Impact factor: 4.599
  8 in total

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