Literature DB >> 18725440

Real-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae.

S Page1, F Vernel-Pauillac, O O'Connor, S Bremont, F Charavay, P Courvalin, C Goarant, S Le Hello.   

Abstract

Fluoroquinolone resistance in Streptococcus pneumoniae mainly involves stepwise mutations predominantly in the parC and gyrA genes. We have developed a single-run real-time PCR assay for detection of the four most common mutations in the quinolone resistance-determining regions of these genes. This assay provides a useful tool for both clinical and epidemiological use.

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Year:  2008        PMID： 18725440      PMCID： PMC2573127          DOI： 10.1128/AAC.00082-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Emergence of fluoroquinolone resistance among multiply resistant strains of Streptococcus pneumoniae in Hong Kong.

Authors:  P L Ho; T L Que; D N Tsang; T K Ng; K H Chow; W H Seto
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

2.  Improving real-time PCR genotyping assays by asymmetric amplification.

Authors:  Kevin Barratt; John F Mackay
Journal:  J Clin Microbiol       Date:  2002-04       Impact factor: 5.948

3.  New real-time PCR assay using locked nucleic acid probes to assess prevalence of ParC mutations in fluoroquinolone-susceptible Streptococcus pneumoniae isolates from France.

Authors:  Jean-Winoc Decousser; Imen Methlouthi; Patrick Pina; Anne Collignon; Pierre Allouch
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

4.  Nonmolecular test for detection of low-level resistance to fluoroquinolones in Streptococcus pneumoniae.

Authors:  Emmanuelle Varon; Serge Houssaye; Sophie Grondin; Laurent Gutmann
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

Review 5.  World-wide development of antibiotic resistance in pneumococci.

Authors:  P C Appelbaum
Journal:  Eur J Clin Microbiol       Date:  1987-08       Impact factor: 3.267

6.  Rapid screening of topoisomerase gene mutations by a novel melting curve analysis method for early warning of fluoroquinolone-resistant Streptococcus pneumoniae emergence.

Authors:  Kazuko Y Fukushima; Yoichi Hirakata; Kazuyuki Sugahara; Katsunori Yanagihara; Akira Kondo; Shigeru Kohno; Shimeru Kamihira
Journal:  J Clin Microbiol       Date:  2006-10-04       Impact factor: 5.948

7.  Fluoroquinolone resistance in Streptococcus pneumoniae: evidence that gyrA mutations arise at a lower rate and that mutation in gyrA or parC predisposes to further mutation.

Authors:  Stephen H Gillespie; Leroy L Voelker; Jane E Ambler; Chris Traini; Anne Dickens
Journal:  Microb Drug Resist       Date:  2003       Impact factor: 3.431

8.  Worldwide incidence, molecular epidemiology and mutations implicated in fluoroquinolone-resistant Streptococcus pneumoniae: data from the global PROTEKT surveillance programme.

Authors:  R Canton; M Morosini; M C Enright; I Morrissey
Journal:  J Antimicrob Chemother       Date:  2003-10-29       Impact factor: 5.790

9.  Fluoroquinolone and macrolide treatment failure in pneumococcal pneumonia and selection of multidrug-resistant isolates.

Authors:  Emilio Pérez-Trallero; José M Marimon; Luis Iglesias; Julián Larruskain
Journal:  Emerg Infect Dis       Date:  2003-09       Impact factor: 6.883

10.  Fluoroquinolone-resistant Streptococcus pneumoniae.

Authors:  Mathias W R Pletz; Randolph V Fugit; Lesley McGee; Jeffery J Glasheen; Darcie L Keller; Tobias Welte; Keith P Klugman
Journal:  Emerg Infect Dis       Date:  2006-09       Impact factor: 6.883
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  3 in total

1.  Rapid detection of a point mutation in the parC gene associated with decreased susceptibility to fluoroquinolones in Mycoplasma bovis.

Authors:  I Lysnyansky; I Mikula; I Gerchman; S Levisohn
Journal:  Antimicrob Agents Chemother       Date:  2009-08-31       Impact factor: 5.191

2.  Multiplex Real-Time Polymerase Chain Reaction-Based Method for the Rapid Detection of gyrA and parC Mutations in Quinolone-Resistant Escherichia coli and Shigella spp.

Authors:  Junyoung Kim; Semi Jeon; Hyungjun Kim; Misun Park; Soobok Kim; Seonghan Kim
Journal:  Osong Public Health Res Perspect       Date:  2012-06

3.  Molecular Investigation of Quinolone Resistance of Quinolone Resistance-Determining Region in Streptococcus pneumoniae Strains Isolated from Iran Using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Method.

Authors:  Mohammad Kargar; Fataneh Moein Jahromi; Abbas Doosti; Somayeh Handali
Journal:  Osong Public Health Res Perspect       Date:  2014-09-06
  3 in total

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